540517-07-5Relevant academic research and scientific papers
Transition metal-catalyzed synthesis of novel biologically relevant tryptophan analogues
Van Esseveldt, Bart C. J.,Van Delft, Floris L.,Smits, Jan M. M.,De Gelder, Rene,Schoemaker, Hans E.,Rutjes, Floris P. J. T.
, p. 823 - 834 (2007/10/03)
A synthetic approach to the synthesis of novel tryptophan derivatives and benzofuran-containing amino acids is detailed. The sequence starts from enzymatically resolved enantiopure acetylene-containing amino acids, of which the acetylene function can be e
Palladium-catalyzed synthesis of novel optically active tryptophan analogues
Van Esseveldt, Bart C. J.,Van Delft, Floris L.,De Gelder, Rene,Rutjes, Floris P. J. T.
, p. 1717 - 1720 (2007/10/03)
(Matrix presented) Both unsaturated proline derivatives and optically active tryptophan analogues have been obtained via Pd-catalyzed cyclization of aniline-containing acetylenic amino acids. The side chain length of the cyclization precursor determines w
