540527-77-3Relevant academic research and scientific papers
Design of new potent and selective secretory phospholipase A2 inhibitors. 6-Synthesis, structure-activity relationships and molecular modelling of 1-substituted-4-[4,5-dihydro-1,2,4-(4H)-oxadiazol-5-one-3-yl(methyl)]-functionalized aryl piperaz
Meddad-Belhabich, Nadia,Aoun, Darina,Djimdé, Atimé,Redeuilh, Catherine,Dive, Georges,Massicot, France,Chau, Fran?ois,Heymans, Fran?oise,Lamouri, Aazdine
supporting information; experimental part, p. 3588 - 3600 (2010/08/05)
The group IIA human non-pancreatic secretory phospholipase A2 (hnp-sPLA2) is one of the enzymes implied in the inflammatory process. In the course of our work on inhibitors of this enzyme we investigated the influence of rigidity of
Novel inhibitor compounds specific of secreted non-pancreatic human a2phospholipase of group II
-
Page/Page column 13, (2010/02/11)
The present invention relates to a compound of the following formula (I) and pharmaceutical compositions containing the compound of formula (I): wherein D, Y, A, B, p, q, W and R have the same meanings as defined in the specification.
