54057-95-3

Usage

Uses

Used in Pharmaceutical Industry:
4-Aminocinnamic acid hydrochloride is used as a key intermediate in the synthesis of various pharmaceuticals for its potential anti-inflammatory, antioxidant, and neuroprotective properties, contributing to the development of drugs with therapeutic benefits.
Used in Organic Compounds Synthesis:
As a derivative of cinnamic acid, 4-aminocinnamic acid hydrochloride is used as a building block in the synthesis of heterocyclic compounds, which are important for their diverse applications in the pharmaceutical industry.
Used in Drug Research and Development:
4-Aminocinnamic acid hydrochloride is utilized in drug research and development as a component with potential therapeutic properties, aiding in the discovery and creation of new drugs with improved efficacy and safety profiles.

InChI:InChI=1/C9H9NO2.ClH/c10-8-4-1-7(2-5-8)3-6-9(11)12;/h1-6H,10H2,(H,11,12);1H/b6-3+;

Upstream product

• 30980-75-7 p-azidocinnamic acid 
• 2393-18-2 p-aminocinnamic acid 

Relevant academic research and scientific papers

The impact of solid solution composition on kinetics and mechanism of [2 + 2] photodimerization of cinnamic acid derivatives

We propose the use of solid solutions for the modulation of the kinetics in [2 + 2] photocycloaddition. Solid solutions with general formula [1H]BrxCl1?x(1= 4-amino-cinnamic acid; 0 x 1) were preparedviamechanochemical methods, structurally characterized, and found to undergo a single-crystal-to-single-crystal [2 + 2] photodimerization. The effect of the solid solution composition on the kinetics was successfully investigatedviaa combination of FTIR and principal component analysis (PCA), and the results were compared with those obtained for the parent materials [1H]Cl and [1H]Br. All systems follow the same nearly first-order law, and the overall reaction kinetics is influenced by a subtle interplay of structural and electronic factors as well as other processes regulating the formation and lifetime of the reacting excimer.

Ultrastrong, Transparent Polytruxillamides Derived from Microbial Photodimers

Ultrastrong and transparent bioplastics are generated from fermented microbial monomers. An exotic aromatic amino acid, 4-aminocinnamic acid, was prepared from a biomass using recombinant bacteria, and quantitatively photodimerized, and diacid and diamino monomers that were both characterized by a rigid α-truxillate structure were generated. These two monomers were polycondensed to create the polyamides with a phenylenecyclobutane repeating backbone such as poly{(4,4′-diyl-α-truxillic acid dimethyl ester) 4,4′-diacetamido-α-truxillamide} which was processed into amorphous fibers and plastic films having high transparency. In spite of noncrystalline structure, mechanical strength of the fiber is 407 MPa at maximum higher than those of other transparent plastics and borosilicate glasses, presumably due to the tentative molecular spring function of the phenylenecyclobutanyl backbone.

Hydrazinium monoformate mediated facile preparation of amines from azides catalyzed by zinc

A variety of functionalized alkyl and aryl primary amines have been prepared from corresponding azides by reaction with hydrazinium monoformate in the presence of low cost commercial zinc dust at room temperature. Many other reducible substituents such as halogen, methoxy, phenol, acid. ethene and nitrile remain unaffected. The hydrogenation is fast, mild, clean, cost-effective and high yielding.