540744-19-2

Upstream product

• 540744-17-0 (-)-(3S)-3-{[(4-methylphenyl)sulfonyl]amino}-N-{(2E)-4-{[(4-methylphenyl)sulfonyl]amino}but-2-enyl}3-phenylpropanamide 
• 357417-35-7 (3S)-3-{[(4-methylphenyl)sulfonyl]amino}-3-phenylpropanoic acid 
• 540744-18-1 (+)-(4S,11E)-5,9-bis[(4-methylphenyl)sulfonyl]-4-phenyl-1,5,9-triazacyclotridec-11-en-2-one 

Relevant academic research and scientific papers

The macrocyclic spermidine alkaloid (-)-(S)-neoperiphylline: Revision of the structure based on the total synthesis

The total synthesis of the two isomeric macrocyclic enamides 2 and 17 is described. The precursor 14 was synthesized by means of template-assisted macrocyclization (Scheme 2). Isomerization of 14 in the presence of [Fe(CO)5] gave 2 and 17 (Sche