540779-20-2Relevant academic research and scientific papers
Analogues of orphan nuclear receptor small heterodimer partner ligand and apoptosis inducer (E)-4-[3-(1-adamantyl)-4-hydroxyphenyl]-3-chlorocinnamic acid. 2. Impact of 3-chloro group replacement on inhibition of proliferation and induction of apoptosis of
Xia, Zebin,Correa, Ricardo G.,Das, Jayanta K.,Farhana, Lulu,Castro, David J.,Yu, Jinghua,Oshima, Robert G.,Fontana, Joseph A.,Reed, John C.,Dawson, Marcia I.
, p. 233 - 249 (2012/03/10)
The parent phenol of adapalene and its (E)-cinnamic acid analogue were found to induce cancer cell apoptosis but cause adverse systemic effects when administered to mice. In contrast, their respective 5-Cl- and 3-Cl-substituted analogues had their adverse
