5408-16-2Relevant academic research and scientific papers
Design, molecular docking, and antimicrobial assessment of newly synthesized phytochemical thymol Mannich base derivatives
Bishoyi, Ajit Kumar,Mahapatra, Monalisa,Padhy, Rabindra Nath,Paidesetty, Sudhir Kumar
, (2021/07/28)
Antibacterial resistance has been brewing for decades and has now surfaced into potential public health emergency, everywhere. Thus, newer potent drug candidates are needed urgently that would help overcoming antibiotic resistances in bacteria and fungi.
Carbonic anhydrase inhibition and cytotoxicity studies of Mannich base derivatives of thymol
Inci Gul, Halise,Yamali, Cem,Tugce Yasa, Asiye,Unluer, Elif,Sakagami, Hiroshi,Tanc, Muhammet,Supuran, Claudiu T.
, p. 1375 - 1380 (2016/10/09)
Mannich bases of thymol were synthesized. The aminomethylation reaction was realised in the ortho position of the phenol for compounds 2 (dipropylamine), 3 (benzylamine), and 4 (dibenzylamine) while it was from para position for 1 (dimethylamine), 5 (pipe
