540803-89-2Relevant academic research and scientific papers
Synthesis of 2-phenylnaphthalenes through gold-catalyzed dimerization via a highly selective carbon nucleophile pathway
Wang, Sinan,Zhang, Lei,Ding, Xiao,Zhou, Yu,Wang, Jinfang,Jiang, Hualiang,Liu, Hong
experimental part, p. 4514 - 4521 (2011/06/27)
A protocol for the facile synthesis of 2-phenylnaphthalene has been developed. The benzyl carbon acts as a nucleophilic center in the presence of the amide nitrogen and acetate oxygen, affording the selective formation of a naphthalene scaffold through th
Branch-selective synthesis of oxindole and indene scaffolds: Transition metal-controlled intramolecular aryl amidation leading to C3 reverse-prenylated oxindoles
Ignatenko, Vasily A.,Deligonul, Nihal,Viswanathan, Rajesh
supporting information; experimental part, p. 3594 - 3597 (2010/11/04)
In an effort to access biologically important scaffolds, a concise branch-selective synthesis of C3 tertiary oxindoles by Cu(I)-catalyzed aryl amidation and 2,2-dimethyl indene by Pd(0)-catalyzed Heck cyclization has been accomplished from acyclic reverse-prenylated intermediates. Oxindole C3-enolate generation using NaH followed by alkylation in the presence of appropriate electrophiles provides a novel route to quaternary C3 reverse-prenylated oxindoles.
