54091-37-1Relevant academic research and scientific papers
Magnetic nano Fe3O4 catalyzed solvent-free stereo- and regioselective a-aminolysis of epoxides by amines; A green method for the synthesis of β-amino alcohols
Kumar, Amit,Parella, Ramarao,Babu, Srinivasarao Arulananda
, p. 835 - 842 (2014/04/17)
We report the use of magnetic nano Fe3O4 as a mild heterogeneous catalyst for the aminolysis of epoxides with amines. The approach constitutes a green method for the formation of a variety of β-amino alcohols with very high stereo- and regioselectivity under solvent-free and ambient reaction conditions. The aminolysis of chiral epoxides with amines gave the corresponding chiral β-amino alcohols with complete inversion of stereochemistry. The magnetic nano Fe3O4 catalyst can be easily recovered and recycled. Georg Thieme Verlag Stuttgart New York.
Regioselectivity in a highly efficient, microwave-assisted epoxide aminolysis
Desai, Hinal,D'Souza, Brendan R.,Foether, Devin,Johnson, Benjamin F.,Lindsay, Harriet A.
, p. 902 - 910 (2008/01/06)
We have developed a microwave-assisted aminolysis of epoxides as an efficient method for synthesizing a number of β-amino alcohols. In most cases, including in reactions of amines with a trisubstituted epoxide, only one equivalent of amine is required to
