54095-25-9Relevant academic research and scientific papers
Large-scale preparation of aromatic fluorides via electrophilic fluorination with functionalized aryl- or heteroarylmagnesium reagents
Yamada, Shigeyuki,Knochel, Paul
experimental part, p. 2490 - 2494 (2010/09/04)
Functionalized aryl- or heteroarylmagnesium reagents, prepared from the corresponding bromides or iodides using halogen-magnesium exchange or direct magnesium insertion in the presence of lithium chloride, reacted smoothly with N-fluorobenzenesulfonimide, (PhSO2)2NF, in the mixed solvent (4:1 CH2Cl2-perfluorodecalin) to give the corresponding aromatic fluorides in moderate to good yields. Georg Thieme Verlag Stuttgart · New York.
Convenient electrophilic fluorination of functionalized aryl and heteroaryl magnesium reagents
Yamada, Shigeyuki,Gavryushin, Andrei,Knochel, Paul
supporting information; experimental part, p. 2215 - 2218 (2010/06/19)
"Chemical Equation Presented" Cive me an "F": Electrophilic fluorination of various aromatic and heteroaromatic Grignard reagents is smoothly performed with (PhSO2)2NF as fluorinating agent in a 4:1 mixture of CH2Cl2/ perfluorodecalin (see scheme). This solvent system allows minimization of most side reactions.
