54110-25-7 Usage
Uses
Used in Pharmaceutical Industry:
Pirozadil is used as a hypolipidemic agent for its ability to improve cerebral blood flow and reduce vascular cerebral resistance, making it a potential treatment option for conditions related to blood flow and lipid levels in the brain.
Used in Neurological Applications:
Pirozadil is used as a therapeutic agent for neurological conditions, where its capacity to enhance cerebral blood flow and lower vascular resistance can contribute to the treatment and management of various brain-related disorders.
Originator
Pemix ,Prodes ,Spain,1982
Manufacturing Process
15 kg (70.7 mols) of 3,4,5-trimethoxybenzoic acid and 65 liters of benzene were introduced into a reactor, to which mixture was added 27.4 liters of thionyl chloride. The mass was heated to 56°C to 70°C during a period of 5 hours. The excess of benzene and thionyl chloride was distilled under vacuum. The residue was kept under vacuum at 120°C to 123°C for 1 hour, to obtain a hard crystalline solid.A solution comprising 3.24 kg (23.3 mols) of pyridine-2,6-dimethanol in 35 liters of pure pyridine was added to the residue and the mass was heated to 80°C for 2? hours. The reaction mass became brown in color. The chlorhydrate of pyridine so formed was cooled and crystallized. The resulting reaction mass was then poured into water. The precipitate obtained was filtered, repeatedly rinsed with water, and dissolved in 400 liters of methanol. The resulting solution was filtered with activated charcoal. From this filtration 50 liters of methanol were distilled at normal pressure and then crystallized. 8.35 kg (15.8 mols) of pyridine-2,6dimethanol trimethoxybenzoate were obtained, which represented a yield of 68%.The product was a white crystalline solid which melted at 119°C to 126°C. Recrystallization in methanolone gave a product which melted at 126°C to 127°C.
Therapeutic Function
Antihyperlipidemic, Platelet aggregation inhibitor
Check Digit Verification of cas no
The CAS Registry Mumber 54110-25-7 includes 8 digits separated into 3 groups by hyphens. The first part of the number,starting from the left, has 5 digits, 5,4,1,1 and 0 respectively; the second part has 2 digits, 2 and 5 respectively.
Calculate Digit Verification of CAS Registry Number 54110-25:
(7*5)+(6*4)+(5*1)+(4*1)+(3*0)+(2*2)+(1*5)=77
77 % 10 = 7
So 54110-25-7 is a valid CAS Registry Number.
InChI:InChI=1/C27H29NO10/c1-31-20-10-16(11-21(32-2)24(20)35-5)26(29)37-14-18-8-7-9-19(28-18)15-38-27(30)17-12-22(33-3)25(36-6)23(13-17)34-4/h7-13H,14-15H2,1-6H3
