54124-75-3Relevant academic research and scientific papers
Hydroxamic acids
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, (2008/06/13)
This invention provides a series of novel hydroxamic acids of formula I which are useful as inhibitors of metalloproteases such as endopeptidases.
Hydroxamic acids
-
, (2008/06/13)
The invention provides a series of novel hydroxamic acids of the formula I which are useful as inhibitors of metalloproteases such as endopeptidases and wherein R1 is a hydrophobic group, R2 and R3 are each an amino acid residue, n is 1 or 2, and A is a group of the formula:-, -CHR4.CO.NH2, in which R4 is an amino acid residue. Also described are processes for the manufacture of the hydroxamic acids, pharmaceutically acceptable salts derived from the said acids and pharmaceutical compositions containing a said acid or salt.
