54127-40-1

Upstream product

• 106-89-8 epichlorohydrin 
• 15128-82-2 3-hydroxy-2-nitropyridine 

Downstream Products

• 282108-01-4 1-benzyloxy-3-(2-nitropyridin-3-yloxy)propan-2-ol 
• 761401-59-6 1-(2-nitropyridin-3-yloxy)-3-(4-phenylpiperazin-1-yl)propan-2-ol 
• 761401-66-5 (2,3-dihydro[1,4]dioxino[2,3-b]pyridin-3-ylmethyl) 4-methylbenzenesulfonate 
• 761401-67-6 (2,3-dihydro[1,4]dioxino[2,3-b]pyridin-2-ylmethyl) 4-methylbenzenesulfonate 
• 258883-71-5 3-(2,3-Dihydro-1,4-dioxino[2,3-b]pyridine)yl-N-methyl-N-benzyl-methanamine 
• 152895-33-5 benzyl-(2,3-dihydro[1,4]dioxino[2,3-b]pyridin-3-ylmethyl)amine 
• 153332-62-8 2,3-dihydro-2-benzyloxymethyl-1,4-dioxino<2,3-b>pyridine 
• 152560-77-5 2,3-dihydro-3-<(phenylmethoxy)methyl>-1,4-dioxino<2,3-b>pyridine 
• 282108-06-9 1-(N-benzylamino)-3-(2-nitropyridin-3-yloxy)propan-2-ol 
• 282108-04-7 1-(N-benzyl-N-methylamino)-3-(2-nitropyridin-3-yloxy)propan-2-ol 

Relevant academic research and scientific papers

Efficient synthesis of 2- and 3-substituted-2,3-dihydro [1,4]dioxino[2,3-b]pyridine derivatives

A versatile new approach for the synthesis in three steps of 2-substituted-2,3-dihydro[1,4]dioxino[2,3-b]pyridines B via a Smiles rearrangement using easily available reagents is described. A study illustrating the influence of experimental conditions on the progress of the reaction is reported.

Synthesis of 2-Substituted-2,3-dihydro-1,4-dioxino[2,3-b]pyridine Derivatives

(Matrix Presented) A variety of 2-substituted-2,3-dihydro-1,4-dioxino[2,3-b]pyridines B have been synthesized from the readily available 2-nitro-3-oxiranylmethoxy-pyridine 1 via a Smiles rearrangement. We demonstrate how variations of reaction conditions

2-(3-Amino-2-hydroxy-propoxy)-mono-and diazines

Heterocyclic compounds of the formula STR1 wherein Het denotes optionally substituted pyridazinyl, pyrimidinyl, pyrazinyl or substituted pyridyl, R1 is hydrogen or methyl and R2 is lower alklyl, optionally substituted phenyl-lower alkyl, carboxy-lower alkyl or functionally modified carboxy-lower alkyl, their condensation products with aldehydes, ketones or carbonic acid and their N-oxides, which are valuable (cardioselective) β-receptor blocking agents, and/or (cardioselective) β-receptor-stimulants.

2-(3-AMINO-2-HYDROXY-PROPOXY)-PYRAZINES

Heterocyclic compounds of the formula STR1 wherein Het denotes optionally substituted pyridazinyl, pyrimidinyl, pyrazinyl or substituted pyridyl, R 1 is hydrogen or methyl and R 2 is lower alkyl, optionally substituted phenyl-lower alkyl, carboxy-lower alkyl or functionally modified carboxy-lower alkyl, their condensation products with aldehydes, ketones or carbonic acid and their N-oxides, which are valuable (cardioselective) β-rezeptor blocking agents, and/or (cardioselective) β-rezeptor-stimulants.