54149-15-4

Usage

Uses

Used in Pharmaceutical Production:
1-Bromo-3-methoxy-butane is used as an intermediate in the production of pharmaceuticals for its ability to facilitate the synthesis of various drug compounds.
Used in Agrochemical Production:
1-Bromo-3-methoxy-butane is used as an intermediate in the production of agrochemicals, contributing to the development of substances that aid in crop protection and enhancement.
Used in Specialty Chemicals Production:
1-Bromo-3-methoxy-butane is used as an intermediate in the production of specialty chemicals, which are important for various industrial applications.
Used in Chemical Research and Development:
1-Bromo-3-methoxy-butane is utilized in research and development within the chemical industry, where it serves as a valuable compound for creating new chemical entities and improving existing processes.
Safety Note:
1-Bromo-3-methoxy-butane is considered to be a flammable and potentially hazardous substance. Therefore, proper safety precautions should be taken when handling and storing it to ensure the safety of individuals and the environment.

Upstream product

• 55524-92-0 1-(tosyloxy)-3-methoxybutane 
• 2517-43-3 3-methoxy butanol 

Relevant academic research and scientific papers

Isolation, Structure Elucidation, and (Bio)Synthesis of Haprolid, a Cell-Type-Specific Myxobacterial Cytotoxin

Myxobacteria are well-established sources for novel natural products exhibiting intriguing bioactivities. We here report on haprolid (1) isolated from Byssovorax cruenta Har1. The compound exhibits an unprecedented macrolactone comprising four modified amino acids and a polyketide fragment. As configurational assignment proved difficult, a bioinformatic analysis of the biosynthetic gene cluster was chosen to predict the configuration of each stereocenter. In-depth analysis of the corresponding biosynthetic proteins established a hybrid polyketide synthase/nonribosomal peptide synthetase origin of haprolid and allowed for stereochemical assignments. A subsequent total synthesis yielded haprolid and corroborated all predictions made. Intriguingly, haprolid showed cytotoxicity against several cell lines in the nanomolar range whereas other cells were almost unaffected by treatment with the compound.

2-Ethoxy-5-alkyl-3,4-dihydro-2H-pyrans in Organic Synthesis: A New Convenient Route to Branched δ-Ethoxy Alcohols

The reaction between 2-ethoxy-5-alkyl-5,6-dichlorotetrahydropyrans and Grignard reagents has been investigated, and the overall results clearly indicate that the reaction provides a useful route to the preparation of highly branched primary, secondary, and tertiary δ-ethoxy alcohols.Experimental evidence is presented to support the occurrence of suitable epoxides as reaction intermediates that may evolve to products either through a pinacol-type isomerization and/or via a cyclic intramolecular rearrangement of a halohydrin halomagnesium salt.