541507-18-0

Basic information

• Product Name: 2-phenethyl-2,3-dihydrofuran
• Synonyms: 2-phenethyl-2,3-dihydrofuran
• CAS NO: 541507-18-0
• Molecular Weight: 174.243
• Mol File: 541507-18-0.mol

Chemical Properties

• CAS DataBase Reference: 2-phenethyl-2,3-dihydrofuran(CAS DataBase Reference)
• NIST Chemistry Reference: 2-phenethyl-2,3-dihydrofuran(541507-18-0)
• EPA Substance Registry System: 2-phenethyl-2,3-dihydrofuran(541507-18-0)

Safety Data

• Hazardous Substances Data: 541507-18-0(Hazardous Substances Data)

Upstream product

• 78808-38-5 1-phenylhexa-4,5-dien-3-ol 
• 191112-45-5 2-(2'-phenylethyl)-2,5-dihydrofuran 
• 541507-39-5 (3-allyloxy-pent-4-enyl)-benzene 
• 37904-38-4 5-phenylpent-1-en-3-ol 
• 104-53-0 3-phenyl-propionaldehyde 

Downstream Products

• 1334240-28-6 2-(4-methoxyphenyl)-5-phenethylfuran 
• 1334240-27-5 (E)-1-(4-methoxyphenyl)-6-phenylhex-2-en-1-one 
• 1334240-29-7 2-(4-methoxy-3-nitrophenyl)-5-phenethylfuran 
• 1334240-30-0 2-phenethyl-5-(3,4,5-trimethoxyphenyl)furan 
• 1334240-31-1 methyl 2-methoxy-5-(5-phenethylfuran-2-yl)benzoate 
• 1222-76-0 2-phenyl-5-phenylethylfuran 

Relevant articles and documents

Cooperative Metal-Ligand Catalyzed Intramolecular Hydroamination and Hydroalkoxylation of Allenes Using a Stable Iron Catalyst

A new iron-catalyzed chemoselective intramolecular hydroamination and hydroalkoxylation of the readily available α-allenic amines and alcohols to valuable unsaturated 5-membered heterocycles, 2,3-dihydropyrrole and 2,3-dihydrofuran, is reported. Effective

Ru- and Pd-catalysed synthesis of 2-arylfurans by one-flask heck arylation/oxidation

2,5-Disubstituted furans were synthesized by one-flask Heck arylation/oxidation sequences. The starting materials are 2-substituted 2,3-dihydrofurans, conveniently available by RCM/isomerization sequences, and arenediazonium salts. These react in ligand-free Heck reactions to afford 2,5-disubstituted 2,5-dihydrofurans, which are oxidized to the corresponding furans without isolation or intermediate workup. The oxidation is conveniently achieved with chloranil or DDQ, depending on the substrate.

Ruthenium-catalyzed olefin metathesis double-bond isomerization sequence

A novel ruthenium-catalyzed tandem ring-closing metathesis (RCM) double-bond isomerization reaction is described in this paper. The utility of this method for the efficient syntheses of five-, six-, and seven-membered cyclic enol ethers is demonstrated. It relies on the conversion of a metathesis-active ruthenium carbene species to an isomerization-active ruthenium-hydride species in situ. This conversion is achieved by using various additives. Scope and limitations of the different protocols are discussed, and some mechanistic considerations based on 31P and 1H NMR spectroscopic studies are presented.

An olefin metathesis/double bond isomerization sequence catalyzed by an in situ generated ruthenium hydride species

The direct conversion of allyl ethers to cyclic enol ethers using an olefin metathesis/double bond migration sequence is described. Ruthenium carbene complexes were activated to catalyze the double bond migration step by addition of hydride sources, such