541508-74-1Relevant articles and documents
Stereoselective synthesis of alicyclic ketones: A hydrogen borrowing approach
Armstrong, Roly J.,Akhtar, Wasim M.,Frost, James R.,Christensen, Kirsten E.,Stevenson, Neil G.,Donohoe, Timothy J.
supporting information, (2019/11/13)
A highly diastereoselective annulation strategy for the synthesis of alicyclic ketones from diols and pentamethylacetophenone is described. This process is mediated by a commercially available iridium(III) catalyst, and provides efficient access to a wide range of cyclopentane and cyclohexane products with high levels of stereoselectivity. The origins of diastereoselectivity in the annulation reaction have been explored by a series of control experiments, which provides an explanation for how each stereocentre around the newly forged ring is controlled.
Asymmetric conjugate addition of malonate to α,β-unsaturated ketones in water using a perfluoroalkanesulfonamide organocatalyst
Kamito, Yuji,Masuda, Akira,Yuasa, Hiroki,Tada, Norihiro,Itoh, Akichika,Nakashima, Kosuke,Hirashima, Shin-Ichi,Koseki, Yuji,Miura, Tsuyoshi
, p. 974 - 979 (2014/08/18)
Perfluoroalkanesulfonamide organocatalyst 7 efficiently promotes asymmetric Michael additions of malonates to enones in cyclohexane or water to produce the corresponding addition products with excellent yields and with up to 99% ee.
Simple chiral sulfonamide primary amine catalysed highly enantioselective Michael addition of malonates to enones
Luo, Chunhua,Jin, Yu,Du, Da-Ming
experimental part, p. 4116 - 4123 (2012/06/15)
A chiral sulfonamide primary amine-organocatalysed, highly enantioselective Michael addition of malonates to enones has been developed. This reaction afforded the corresponding products in excellent yields (up to 99%) and excellent enantioselectivity (up
