54185-32-9Relevant academic research and scientific papers
Synthesis and biological activity evaluation of novel imidazolidinedione derivatives, as potent antidiabetic agent
Wang, Run-Ling,Li, Wen-Ming,Liu, Meng-Yuan,Xu, Wei-Ren
experimental part, p. 34 - 39 (2010/04/26)
A set of novel imidazolidinedione derivatives were synthesized and evaluated as potential antidiabetic agents. Imidazolidinedione scaffold-based molecules were synthesized and validated on a mice hyperglycemia model caused by alloxan. As a result, three of them showed antihyperglycemic activities. This research provides useful clues for further design and discovery of antidiabetic agents.
