54210-98-9Relevant academic research and scientific papers
Nonselective bromination-selective debromination strategy: Selective bromination of unsymmetrical ketones on singly activated carbon against doubly activated carbon
Choi, Han Young,Chi, Dae Yoon
, p. 411 - 414 (2007/10/03)
(Matrix presented) We have found a new synthetic method for the preparation of the α-bromoketones that are brominated in the less activated terminal position of unsymmetrical ketones. Brominations in short reaction times (kinetically controlled) provided internally brominated compounds as a major product. However, brominations in longer reaction times (thermodynamically controlled) gave more of the terminally brominated compound through the reversible reaction by Br2 and produced hydrogen bromide. Several brominated compounds at the terminal position were successfully prepared through the new synthetic route.
Formation of α-iminoketones and α-diimines versus Favorskii rearrangement products from the reaction of α,α′-dibromoketones and primary amines
De Kimpe, Norbert,D'Hondt, Luc,Mones, Luc
, p. 3183 - 3208 (2007/10/02)
The reaction of aliphatic acyclic α,α'-dibromoketones with primary amines gave rise to α-iminoketones and α-diimines. Both reaction products could be selectively obtained under appropriate reaction conditions. Sterically hindered α,α-dibromoketones did no
STEREOSELECTIVE PREPARATION OF METHYL (Z)-CINNAMATES BY FAVORSKII REARRANGEMENT
Engler, Thomas A.,Falter, Wolfgang
, p. 4119 - 4120 (2007/10/02)
1,3-Dibromo-1-phenylacetones, readily prepared by direct bromination of the parent phenylacetone, react with methanolic sodium methoxide to yield stereoselectively methyl (Z) cinnamates in good yield.
NOVEL BROMINATION REAGENTS. HEXABROMOCYCLOPENTADIENE: BROMINATION OF ACTIVATED SATURATED SITES
Magen, Shulamit,Oren, Jakob,Fuchs, Benzion
, p. 3369 - 3372 (2007/10/02)
Hexabromocyclopentadiene (HBC) readily brominates α-keto and benzylic sites, apparently by bromonium ion transfer.
