54211-97-1Relevant articles and documents
Pyrido[1,2-a]pyrimidone analogs as PI3K inhibitors
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Paragraph 0370; 0375; 0376; 0377, (2016/10/08)
The present invention discloses a class of pyrido[1,2-a]pyrimidone analogs as PI3K inhibitors, and particularly relates to a compound represented by a formula (I) or a pharmaceutically acceptable salt thereof. The formula (I) is defined in the specification.
α-Amino-α-vinyl-γ-butyrolactone derivatives from α-{[(trimethylsilyl)-methyl]alkylidene}-γ-butyrolactones
Capuzzi, Marinella,Gambacorta, Augusto,Gasperi, Tecla,Loreto, M. Antonietta,Tardella, P. Antonio
, p. 5076 - 5082 (2007/10/03)
N-Protected α-amino-α-vinyl-γ-butyrolactones 1 are obtained by the aza-Michael-type addition of NsONHCO2Et to novel silylated α-ylidene-γ-butyrolactones 2, through ring opening of the intermediate aziridine and loss of the trimethylsilyl group.
Diastereoselective hydrogenations of α-alkyl α-(2,3,4,6-tetra-O-acetyl-β-D-glucopyranosyloxy)methylene carbonyl compounds. New route to stereopure α-alkyl α-oxymethyl carbonyl compounds
Larsen, David S.,Schofield, Anthony,Stoodley, Richard J.,Tiffin, Peter D.
, p. 2487 - 2495 (2007/10/03)
Wittig condensation of the stabilised phosphoranes 9, 10 and 26 with 1-formyl-2,3,4,6-tetra-O-acetyl-β-D-glucopyranose 11 leads to the vinylogous carbonates 12, 13 and 22. The salts 27-30 and 44, prepared from the corresponding carbonyl compounds, ethyl f