5422-50-4

Usage

Uses

Used in Pharmaceutical Industry:
1-bromo-2-[(2-methylphenoxy)methyl]benzene is utilized as a key intermediate in the synthesis of pharmaceuticals, contributing to the development of new medications due to its unique chemical structure and reactivity.
Used in Agrochemical Industry:
In the agrochemical sector, 1-bromo-2-[(2-methylphenoxy)methyl]benzene is employed as an intermediate for the production of various agrochemicals, playing a part in the creation of substances that protect crops and enhance agricultural productivity.
Used in Fine Chemicals Production:
1-bromo-2-[(2-methylphenoxy)methyl]benzene also serves as an intermediate in the manufacturing process of fine chemicals, which are high-purity chemicals used in various applications such as fragrances, flavors, and dyes.
Used in Specialty Chemicals Manufacturing:
1-bromo-2-[(2-methylphenoxy)methyl]benzene is used as a building block in the production of specialty chemicals, which are often applied in specific industries for their unique properties and functions.

Upstream product

• 578-51-8 2-bromobenzylchloride 
• 95-48-7 ortho-cresol 
• 3433-80-5 1-Bromo-2-bromomethyl-benzene 

Downstream Products

• 181643-18-5 2-[2-(2-methylphenoxymethyl)-benzoyl]-pyridine 
• 117712-97-7 4,4'-di(s-butyl)biphenyl 
• 19578-70-2 benzyl 2-methylphenyl ether 
• 19482-16-7 4,4'-dichloro-3,3'-dimethyl-1,1'-biphenyl 
• 1591-30-6 (1,1'-biphenyl)-4,4'-dicarbonitrile 
• 7168-54-9 4,4'-diethoxybiphenyl 
• 47230-38-6 diethyl biphenyl-4,4'-dicarboxylate 
• 6279-13-6 4-(2-bromo-benzyl)-2-methyl-phenol 

Relevant academic research and scientific papers

Neocuproine-KOtBu promoted intramolecular cross coupling to approach fused rings

Polycycles can be produced with different linkages (A, B = O, N, C, S) by constructing biaryl C-C bonds via neocuproine-KOtBu promoted cross coupling between C-Xs and C-Hs.

A novel method for the efficient synthesis of methyl 2-oxo-2- arylacetates and its application to the preparation of fungicidal methyl (E)- O-methyloximino-2-arylacetates and their (Z)-stereoisomers

Methyl 2-oxo-2-arylacetates 1, which include some fluorinated compounds, have been synthesized in moderate to excellent yields by reaction of methyl oxalyl chloride with arylzinc halides in the presence of Pd(PPh3)4. The highest yields have been obtained when these reactions involved arylzinc bromides which were prepared by conversion of the corresponding aryl bromides to organolithiums, followed by transmetallation with ZnBr2. Compounds 1 have been converted in high yields to the corresponding (E)- and (Z)-O- methyloximino-2-arylacetates (E)- and (Z)-5 by treatment with O- methylhydroxylamine hydrochloride in pyridine. Compounds (E)- and (Z)-5 have been easily separated by MPLC on silica gel and their structure and stereochemistry have been assigned by NMR techniques. So prepared compounds of general formula 5 included an agrochemically important fungicide, i.e. (E)-5c, its fluorinated structural analogues, as well as compounds which proved to be able to delay the growth of fungal species isolated from deteriorated papers. Interestingly, several compounds of general formula (Z)- 5 underwent partial stereomutation in the presence of daylight and catalytic amounts of iodine.

Process for the preparation of arylacetic ester derivatives via palladium-catalyzed cross coupling reaction

Process for the preparation of 2-methoxyimino-2-arylacetic esters of formula (I) in which R is C1 -C12 alkyl, which comprises reacting an appropriately substituted boronic acid of general formula (II) or the trimeric form (lII) herei

β-substituted cinnamic acid derivative

β-Substituted cinnamic acid derivatives of the formula 1, STR1 where R1 is substituted or unsubstituted alkyl, alkenyl, alkynyl, cycloalkyl or cycloalkenyl, and R1 can also be chlorine or bromine, --X-- is --O--, --S--, STR2 m is 0 or 1, --Y is --OR4, --O--N=CR5 R6, --NR7 R8, --NR7 R8, --N(OR9)R10 or SR11, where the abovementioned substitutes R2 to R11 are substituted or unsubstituted alkyl, alkenyl, alkynyl, cycloalkyl or cycloalkenyl, and R2, R3 and R5 to R11 can be hydrogen and Z, U, V, W are defined in the specification.