54221-73-7 Usage
Uses
Used in Pharmaceutical Research and Development:
4-Chloro-3H-imidazo[4,5-c]pyridin-2-ol is used as a research tool for the development of new drugs targeting obesity and metabolic disorders. Its agonistic action on beta-3 adrenergic receptors in fat cells facilitates the breakdown of stored fat, offering a potential therapeutic approach to weight management and related health issues.
Used in Metabolic Disorder Treatment:
In the field of metabolic research, 4-Chloro-3H-imidazo[4,5-c]pyridin-2-ol is used as a potential therapeutic agent for improving glucose and lipid metabolism. Its ability to influence these metabolic pathways positions it as a candidate for the treatment of conditions such as diabetes and dyslipidemia.
Used in Obesity Treatment:
4-Chloro-3H-imidazo[4,5-c]pyridin-2-ol is used as a potential treatment for obesity, leveraging its capacity to stimulate beta-3 adrenergic receptors and promote the breakdown of fat. This mechanism could contribute to weight loss and the mitigation of obesity-related health complications.
Further research is necessary to fully elucidate the mechanisms of action and potential side effects of 4-Chloro-3H-imidazo[4,5-c]pyridin-2-ol, ensuring its safe and effective application in clinical settings.
Check Digit Verification of cas no
The CAS Registry Mumber 54221-73-7 includes 8 digits separated into 3 groups by hyphens. The first part of the number,starting from the left, has 5 digits, 5,4,2,2 and 1 respectively; the second part has 2 digits, 7 and 3 respectively.
Calculate Digit Verification of CAS Registry Number 54221-73:
(7*5)+(6*4)+(5*2)+(4*2)+(3*1)+(2*7)+(1*3)=97
97 % 10 = 7
So 54221-73-7 is a valid CAS Registry Number.
InChI:InChI=1/C6H4ClN3O/c7-5-4-3(1-2-8-5)9-6(11)10-4/h1-2H,(H2,9,10,11)
54221-73-7Relevant academic research and scientific papers
Aza-BODIPY Route to Ageladine A
Fresia, Marvin,Lindel, Thomas,Tolle, Christian
supporting information, p. 1308 - 1312 (2022/02/23)
The marine natural product ageladine A was synthesized by exploiting novel aza-BODIPY-type boron complexes that allowed the regioselective dibromination of the pyrrole unit, as confirmed by quantum chemical calculation (ωB97XD/TApr-cc-pVDZ). The parent tricycle was accessed by Suzuki-Miyaura cross-coupling employing Buchwald’s precatalyst. The boron complex of ageladine A exhibited strong fluorescence that was greater than that of the natural product by a factor of ～30 and that disappeared in the presence of 2-azido groups.
PHENYLUREA DERIVATIVES USED AS INHIBITORS OF TYROSINKINASE FOR TREATING TUMORS
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Page/Page column 59-60, (2008/06/13)
The invention relates to the compounds of formula (I), wherein R1a-R1e, R2a, R2b, R3 and X are defined as in claim 1. The inventive derivatives are tyrosinkinase inhibitors, especially inhibitors of TIE-2, and Raf kinase inhibitors and may inter alia be used for treating tumors.
SYNTHESIS AND PROPERTIES OF 4-HALOIMIDAZOPYRIDIN-2-ONES
Yutilov, Yu.M.,Svertilova, I.A.
, p. 923 - 927 (2007/10/02)
The nitro group in 4-nitroimidazopyridin-2-ones is rather labile and may be reploaced upon heating with hydrohalic acids to give the corresponding 4-halides.A methyl group at N(3) leads to a sharp increase in the lability of the nitro gr
