54244-74-5Relevant academic research and scientific papers
A Low Rhodium Content Smart Catalyst for Hydrogenation and Hydroformylation Reactions
Paganelli, Stefano,Tassini, Riccardo,Rathod, Vikas D.,Onida, Barbara,Fiorilli, Sonia,Piccolo, Oreste
, p. 1508 - 1521 (2020/10/15)
Abstract: This paper describes the preparation, broad characterization and study of activity in hydrogenation and hydroformylation reactions of an easily produced 0.18% Rh/Al2O3. Analytical studies on fresh and recycled samples shed light on the smart properties of such catalyst. Results showed high activity as well as fine/excellent chemoselectivity or regioselectivity, characteristics that may suggest a wide range of applicability. Graphic Abstract: The low metal content catalyst 0.18% Rh/Al2O3 was very active in both hydrogenation and hydroformylation reactions so providing intermediates for valuable APIs, as Nabumetone and Eletriptan, and a fragrance with a fresh, green-floral smell, that recalls scent of lily of the valley.[Figure not available: see fulltext.]
Characterization of initial reaction intermediates in heated model systems of glucose, glutathione, and aliphatic aldehydes
Wang, Tianze,Zhen, Dawei,Tan, Jia,Xie, Jianchun,Cheng, Jie,Zhao, Jian
, (2019/09/12)
To understand the effect of lipid degradation on Maillard formation of meaty flavors, initial reaction intermediates in model systems of glucose–glutathione with hexanal, (E)-2-heptenal, or (E,E)-2,4-decadienal were identified by HPLC–MS and by NMR. Besides Amadori compounds, hemiacetals and thiazolidines via addition of sulfhydryl to carbonyl or to the conjugated olefinic bond were found. Concentrations of all intermediates increased with reaction time while degradation of the intermediates with a glutathione moiety helped formation of thiazolidines with cysteinylglycine. The unsaturated aldehydes (E)-2-heptenal and (E,E)-2,4-decadienal exhibited high reactivity against glucose for glutathione, yielding higher levels of intermediate compounds than from glucose. Heating prepared intermediates reversibly released the original aldehydes, which caused various compounds formed by retro-aldol, oxidation, etc. to react with H2S and NH3. Among them, formation pathways including 3-nonen-2-one, 2-hexanoylfuran, and six dialkylthiophenes (e.g., 2-ethyl-5-(1-methylbutyl)thiophene) were proposed for the first time.
INVESTIGATION OF THE MECHANISM OF THE RECYCLIZATION OF FURANS TO THIOPHENES AND SELENOPHENES UNDER ACID-CATALYSIS CONDITIONS. 3. INVESTIGATION OF THE RECYCLIZATION OF HOMOLOGS AND FUNCTIONAL DERIVATIVES OF FURAN. QUANTUM-CHEMICAL CALCULATIONS OF THE OBJECTS OF THE RECYCLIZATION
Gubina, T. I.,Labunskaya, V. I.,Pankratov, A. N.,Trushin, S. A.,Kharchenko, V. G.
, p. 1393 - 1398 (2007/10/02)
The kinetics of the conversion of di-, tri-, and tetraalkylfurans to the corresponding thiophenes were investigated.A correlation between the reactivities and structures of the investigated furans was established.Quantum-chemical calculations of the objects of the recyclization were made.The calculated and experimental data on the reactivities of the investigated compounds were compared.The most likely pathway of the protonation of furans in their recyclization was determined on the basis of calculations of the total energies of the protonated forms.
