54255-48-0Relevant academic research and scientific papers
Oxidative dimerization of aromatic amines using tBuOI: Entry to unsymmetric aromatic azo compounds
Takeda, Youhei,Okumura, Sota,Minakata, Satoshi
, p. 7804 - 7808 (2012)
It's all the hype: An oxidative dimerization reaction of aromatic amines utilizing tert-butyl hypoiodite (tBuOI) under mild reaction conditions leads to aromatic azo compounds (see scheme). The method allows access to unsymmetric aromatic azo compounds, which are difficult to prepare by conventional synthetic methods, in a selective manner. Copyright
Oxidative dimerization of (hetero)aromatic amines utilizing t-BuOI leading to (hetero)aromatic azo compounds: Scope and mechanistic studies
Okumura, Sota,Lin, Chun-Hsuan,Takeda, Youhei,Minakata, Satoshi
, p. 12090 - 12105 (2014/01/06)
A straightforward synthetic method of both symmetric and unsymmetric aromatic azo compounds through an efficient and cross-selective oxidative dimerization of aromatic amines using tert-butyl hypoiodite (t-BuOI) under metal-free and mild conditions has been developed. This method was also found applicable to the synthesis of heteroaromatic azo compounds. The spectroscopic study indicates the involvement of N,N-diiodoanilines in the oxidative reaction as the key intermediate.
