54259-06-2Relevant academic research and scientific papers
Acetic acid derivatives and processes for their production
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, (2008/06/13)
A process for the preparation of a compound of formula: STR1 wherein R is an amino, hydrocarbylamino or dihydrocarbylamino radical, the hydrocarbylamino and dihydrocarbylamino radicals being unsubstituted, or substituted in the hydrocarbyl moiety with atoms or radicals which do not interfere with the process and Z is an acyl radical which comprises the steps of: (a) decarboxylating a compound of formula: STR2 to produce the corresponding 4-hydroxy-6-methyl-pyrimidine; and (B) TREATING THE CORRESPONDING 4-HYDROXY-6-METHYL PYRIMIDINE THUS PRODUCED WITH AN ACYLATING AGENT CAPABLE OF PROVIDING THE ACYL RADICAL Z; where both steps (a) and (b) are carried out in the same solvent or diluent.
