54287-98-8Relevant academic research and scientific papers
A One-Pot Synthesis of Pyranocoumarins Through Microwave-Promoted Propargyl Claisen Rearrangement/Wittig Olefination
Schmidt, Bernd,Schultze, Christiane
supporting information, p. 223 - 227 (2018/01/26)
The reaction between propargyl ethers of hydroxybenzaldehydes and the ylide ethyl (triphenylphosphoranylidene)acetate was carried out under microwave irradiation to regioselectively afford angular pyranocoumarins. The chromene and coumarin heterocyclic scaffolds were simultaneously formed in the same synthetic step without changing the reaction conditions. The natural products seselin, braylin, and dipetalolactone were among the products synthesized by this method.
Concise modular asymmetric synthesis of deguelin, tephrosin and investigation into their mode of action
Garcia, Jose,Barluenga, Sofia,Beebe, Kristin,Neckers, Len,Winssinger, Nicolas
supporting information; experimental part, p. 9767 - 9771 (2010/10/21)
(Figure Presented) The concise nature and modularity of the synthesis described for deguelin and tephrosin (retrosynthetic analysis depicted) should facilitate access to labeled analogues to dissect the mechanism of action of this important pharmacophore.
Convenient Two-step Syntheses of Seselin and Angelicin Derivatives
Mali, Raghao S.,Pandhare, Nalini A.,Sindkhedkar, Milind D.
, p. 7109 - 7110 (2007/10/02)
Convenient two-step approaches are described for the syntheses of seselin (3a), seselin and angelicin derivatives (3b-d and 5a-d) from 2,4-dihydrobenzaldehyde (1a) and 2,4-dihydroxyacetophenone (1b) using tandem Claisen rearrangement and Wittig reaction.
