54300-37-7Relevant academic research and scientific papers
Copper-catalyzed P-arylation via direct coupling of diaryliodonium salts with phosphorus nucleophiles at room temperature
Xu, Jian,Zhang, Pengbo,Gao, Yuzhen,Chen, Yiyin,Tang, Guo,Zhao, Yufen
, p. 8176 - 8183 (2013)
A new method for copper-catalyzed P-C bond formation through reaction of phosphorus nucleophiles with diaryliodonium salts at room temperature is described. Most target products are obtained with this method in high yields within a short reaction time of 10 min. It can be easily adapted to large-scale preparations. When unsymmetrical iodonium salts are employed, nucleophilic substitution occurs preferentially on the sterically hindered aromatic ring or the more electron-deficient ring.
