54301-05-2

Upstream product

• 623-27-8 terephthalaldehyde, 
• 70277-75-7 lithium acetylide 
• 74-86-2 acetylene 
• 4301-14-8 acetylenemagnesium bromide 
• 501072-65-7 1,4-bis(1-hydroxy-3-trimethylsilylprop-2-ynyl)benzene 

Downstream Products

• 35487-33-3 p-dipropynoylbenzene 
• 1307886-15-2 1,1'-(1,4-phenylene)bis(5-methylhex-5-en-2-yn-1-ol) 
• 1361960-14-6 1,4-bis(3-mesitylpropa-1,2-dienyl)benzene 
• 192577-66-5 ((CO)5W)2((C(OCH₃)CHCH)2C₆H₄) 

Relevant academic research and scientific papers

COMPOUND AND HARDMASK COMPOSITION, HARDMASK LAYER AND METHOD OF FORMING PATTERNS

The present invention relates to a compound represented by chemical formula 1, a hard mask composition containing the compound, a hard mask layer containing a cured product of the hard mask composition, and a pattern forming method using the hard mask com

Trifluorosulfonylation Cascade in Allenols: Stereocontrolled Synthesis of Bis(triflyl)enones

Herein, we report investigations embodying the first example of reversal of the native regioselectivity in the reaction of allenols with electrophiles. The effortlessness of C?C bond formation, mild reaction conditions, neither catalysts nor light irradiation, and exquisite selectivity, both in terms of functional-group tolerance and chemo-, site-, and stereo-selectivity, converts this trifluorosulfonylation-rearrangement sequence into an appealing protocol for the preparation of novel functionalized enones. The synthetic utility of this method has been validated by the conversion of the initially prepared bis(triflyl)enones into a variety of bis(triflyl)-functionalized molecules such as 1,3-dienes, allylic alcohols, pyrroles, pyrazoles, and chromenes. Besides, DFT calculations have provided a reliable understanding of observed selectivity.

Gold-Catalyzed Dehydrogenative Cycloisomerization of 1,4-Enyne Esters to 3,5-Disubstituted Phenol Derivatives

A method to prepare synthetically important 3,5-disubstituted phenol derivatives that relies on the sequential gold(I)-catalyzed dehydrogenative cycloisomerization of 1,4-enyne esters in the presence of 2,3-dichloro-5,6-dicyanobenzoquinone (DDQ) or N-fluorobenzenesulfonimide (NFSI) is described. The synthetic versatility of the methodology was exemplified by a gram-scale reaction of one example, the ease to realize subsequent functional transformations of an adduct, and the application of the method to the synthesis of the bioactive molecule LUF5771. (Figure presented.).

Synthesis of allenes via gold-catalyzed intermolecular reaction of propargylic alcohols and aromatic compounds

Functionalized allenes are efficiently synthesized in moderate to high yield from gold-catalyzed intermolecular reaction of propargylic alcohols and aromatic compounds. The user-friendly process could be conducted under mild reaction conditions with easily accessible starting materials.

Electrophilic carbocyclization of hydroxylated enynes

Mild, efficient, and clean! Six-membered cyclic products including diiodocyclohexadiene and 2,3-diiodobenzene have been prepared in a iodonium-induced internal carbocyclization of hydroxylated enynes (see scheme). This reaction proceeds smoothly under mild reaction conditions, and all the halogen atoms (I and Br) generated from the electrophiles are used effectively.

Rapid preparation of 3-deoxyanthocyanidins and novel dicationic derivatives: New insight into an old procedure

Common 3-deoxyanthocyanidins and original dicationic flavylium- benzopyrylium derivatives are easily and efficiently synthesized through reactions between the corresponding phenols and aryl ethynyl ketones in the presence of aqueous hexafluorophosphoric acid. The mechanism of the reaction is discussed and two competitive pathways are consistent with our results. Wiley-VCH Verlag GmbH & Co. KGaA, 2007.

Functionalised alkenylcarbene metal complexes (M=Ru, W, Cr) by activation of propargyl alcohol derivatives

The reaction of arene ruthenium(II) complexes [Ru(η6-C6Me4R2)(PMe 3)Cl2] (1, R=Me; 1′, R=H) with propargyl alcohol derivatives HCC(H)(OH)(p-C6H4-X) (a, X=HCC(H)(OH); c, X=CHO; d, X=CH=CH2; e, X=CH=CH-CH=CH2) and methanol gives the (methoxy)-alkenylcarbene ruthenium complexes [Ru(η6-C6Me4R2)(PMe 3)(Cl) (=C(OMe)(CH=CH-p-C6H4-X)][PF6] (2a) and (2′c-e). Similarly, the half-sandwich carbene complexes [Ru(η5-C5H5)(CO)(PPh 3)(=C(OMe)(CH=CH-p-C6H4-X)][BF4] (4a and 4d) are obtained from [Ru(η5-C5H5)(CO)(PPh3)(Cl)] (3) and propargyl alcohol derivatives a and d, respectively. Treatment of M(CO)5(THF) (M=W, Cr) with a and HCC(H)(OH)-C4H2S-(OH)(H)CCH (b) yields the monometallic complexes (CO)5M=C(OMe)(=C(OMe)(CH=CH-Ar-(OH)(H)CCH)] (5a) (M=W; -Ar-=-C6H4-), 5b (M=W; -Ar-=-C4H2S-), and 7a (M=Cr; -Ar-=-C6H4-) as the major products, and the bimetallic complexes (CO)5W=C(OMe)CH=CH-Ar-CH=CH(OMe)C=W(CO)5 (6a) and (6b) as the minor products. Finally, the reaction of 5a and 5b with amines (iPrNH2, Me2NH, Et2NH), and diamines such as ethylene diamine and piperazine produces the expected amino alkenyl-tungsten complexes 9a-13a and 9b in high yields.

Synthesis of mixed bis(alkenylcarbene) ditungsten complexes by sequential activation of dialkynols

The synthesis of new bis(alkenylcarbene) ditungsten complexes 2a-b, 5a and 6a has been achieved from W(CO)5(THF), via activation of the dialkynol derivatives a and b. The reaction of 5a with piperazine affords a dissymmetric bis(aminocarbene) complex 7a.