543697-92-3

Upstream product

• 464189-09-1 (4R,5R)-di-tert-butyl 2,2-dioxo-1,3,2-dioxathiolane-4,5-dicarboxylate 2,2-dioxide 
• 157594-60-0 (R)-di-tert-butyl 2-hydroxysuccinate 
• 98-59-9 p-toluenesulfonyl chloride 
• 543697-90-1 (R)-tert-butyl 3,4-dihydroxybutyrate 

Downstream Products

• 543697-99-0 (R)-tert-butyl 3-(4-{4-[bis(2-chloroethyl)amino]phenyl}butyryloxy)-4-[N,N-bis(2-tert-butyldiphenylsilyloxyethyl)amino]butyrate 
• 543697-97-8 (R)-tert-butyl 3-octanoyloxy-4-[N,N-bis(2-tert-butyldiphenylsilyloxyethyl)amino]butyrate 
• 543697-98-9 (R)-tert-butyl 3-phenylacetyloxy-4-[N,N-bis(2-tert-butyldiphenylsilyloxyethyl)amino]butyrate 
• 543697-96-7 (R)-tert-butyl 3-propionyloxy-4-[N,N-bis(2-tert-butyldiphenylsilyloxyethyl)amino]butyrate 
• 543697-95-6 (R)-tert-butyl 3-acetyloxy-4-[N,N-bis(2-tert-butyldiphenylsilyloxyethyl)amino]butyrate 
• 543697-94-5 (R)-tert-butyl 3-hydroxy-4-[N,N-bis(2-tert-butyldiphenylsilyloxyethyl)amino]butyrate 
• 543698-08-4 3-(4-{4-[bis-(2-chloro-ethyl)-amino]-phenyl}-butyryloxy)-4-[bis-(2-hydroxy-ethyl)-amino]-butyric acid tert-butyl ester 
• 543698-03-9 (R)-tert-butyl 3-(4-{4-[bis(2-chloroethyl)amino]phenyl}butyryloxy)-4-[N,N-bis(2-chloroethyl)amino]butyrate 
• 543698-07-3 4-[bis-(2-hydroxy-ethyl)-amino]-3-phenylacetoxy-butyric acid tert-butyl ester 
• 543698-02-8 (R)-tert-butyl 3-phenylacetyloxy-4-[N,N-bis(2-chloroethyl)amino]butyrate 

Relevant academic research and scientific papers

New nitrogen mustards structurally related to (L)-carnitine

Enantiopure nitrogen mustards which mimic (L)-carnitine framework are prepared by a multi-step synthesis from the (R)-di-tert-butyl malate and their antitumor properties evaluated.