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2-(2,5-dioxoimidazolidin-4-yl)ethanesulfonyl chloride is a chemical compound with the molecular formula C4H6ClN2O4S. It is a white crystalline solid that is soluble in water and various organic solvents. 2-(2,5-dioxoimidazolidin-4-yl)ethanesulfonyl chloride is primarily used as a reagent in organic synthesis, particularly in the preparation of sulfonyl-containing compounds and as a protecting group in peptide synthesis. It is also known for its use in the synthesis of certain pharmaceuticals and agrochemicals. Due to its reactivity, it is important to handle this chemical with care, following appropriate safety protocols to minimize potential hazards.

5437-54-7

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5437-54-7 Usage

Chemical structure

2-(2,5-dioxoimidazolidin-4-yl)ethanesulfonyl chloride is a sulfonyl chloride derivative with the chemical formula C5H8ClO4S.

Reactivity

Due to the presence of the sulfonyl chloride group, 2-(2,5-dioxoimidazolidin-4-yl)ethanesulfonyl chloride is highly reactive and can readily undergo nucleophilic substitution reactions.

Functional group introduction

2-(2,5-dioxoimidazolidin-4-yl)ethanesulfonyl chloride is commonly used in organic synthesis to introduce sulfonyl groups into organic molecules, which can enhance the reactivity and stability of the resulting compounds.

Use in pharmaceutical and agrochemical production

2-(2,5-dioxoimidazolidin-4-yl)ethanesulfonyl chloride is widely used in the production of pharmaceuticals and agrochemicals due to its ability to form strong covalent bonds with various functional groups.

Role in the development of new materials

This chemical has been used in the development of new materials, such as polymers and catalysts, due to its unique chemical properties.

Use as a reagent in organic chemistry

2-(2,5-dioxoimidazolidin-4-yl)ethanesulfonyl chloride is a valuable reagent in organic chemistry reactions, particularly in the synthesis of sulfonamides and other sulfur-containing compounds.

Importance in the chemical and pharmaceutical industries

2-(2,5-dioxoimidazolidin-4-yl)ethanesulfonyl chloride plays a crucial role in the advancement of the chemical and pharmaceutical industries, as it enables the synthesis of a wide range of important compounds.

Check Digit Verification of cas no

The CAS Registry Mumber 5437-54-7 includes 7 digits separated into 3 groups by hyphens. The first part of the number,starting from the left, has 4 digits, 5,4,3 and 7 respectively; the second part has 2 digits, 5 and 4 respectively.
Calculate Digit Verification of CAS Registry Number 5437-54:
(6*5)+(5*4)+(4*3)+(3*7)+(2*5)+(1*4)=97
97 % 10 = 7
So 5437-54-7 is a valid CAS Registry Number.

5437-54-7SDS

SAFETY DATA SHEETS

According to Globally Harmonized System of Classification and Labelling of Chemicals (GHS) - Sixth revised edition

Version: 1.0

Creation Date: Aug 19, 2017

Revision Date: Aug 19, 2017

1.Identification

1.1 GHS Product identifier

Product name 2-(2,5-dioxoimidazolidin-4-yl)ethanesulfonyl chloride

1.2 Other means of identification

Product number -
Other names -

1.3 Recommended use of the chemical and restrictions on use

Identified uses For industry use only.
Uses advised against no data available

1.4 Supplier's details

1.5 Emergency phone number

Emergency phone number -
Service hours Monday to Friday, 9am-5pm (Standard time zone: UTC/GMT +8 hours).

More Details:5437-54-7 SDS

5437-54-7Relevant academic research and scientific papers

1-SULPHONYL PIPERIDINE DERIVATIVES

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Page 47-48, (2010/02/06)

Piperidine derivatives of formula (1) that are useful in the inhibition of metalloproteinases, in particular TNF-α Converting Enzyme (TACE) and thus in the treatment of autoimmune disease, allergic/atopic diseases, transplant rejection, graft versus host disease, cardiovascular disease, reperfusion injury and malignancy.

SULPHONAMIDE DERIVATIVES AND THEIR USE AS TACE INHIBITORS

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Page 59-60, (2010/02/06)

Sulphonamide derivatives that are useful in the inhibition of metalloproteinases and in particular in the inhibition of TNF-α Converting Enzyme (TACE).

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