543708-58-3Relevant academic research and scientific papers
Use of a pharmacophore model to discover a new class of influenza endonuclease inhibitors
Parkes, Kevin E. B.,Ermert, Philipp,F?ssler, Jürg,Ives, Jane,Martin, Joseph A.,Merrett, John H.,Obrecht, Daniel,Williams, Glyn,Klumpp, Klaus
, p. 1153 - 1164 (2007/10/03)
Data from both our own and literature studies of the biochemistry and inhibition of influenza virus endonuclease was combined with data on the mechanism of action and the likely active site mechanism to propose a pharmacophore. The pharmacophore was used
