543713-56-0Relevant academic research and scientific papers
SUBSTITUTED PYRIDIZINONE DERIVATIVES AS PDE10 INHIBITORS
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Page/Page column 57, (2014/09/29)
The present invention is directed to substituted pyridizinone compounds of formula (I) which are useful as therapeutic agents for the treatment of central nervous system disorders associated with phosphodiesterase 10 (PDE10). The present invention also relates to the use of such compounds for treating neurological and psychiatric disorders, such as schizophrenia, psychosis or Huntington's disease, and those associated with striatal hypofunction or basal ganglia dysfunction.
SUBSTITUTED PYRIDIZINONE DERIVATIVES AS PDE10 INHIBITORS
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Page/Page column 57, (2014/10/04)
The present invention is directed to substituted pyridizinone compounds of formula I which are useful as therapeutic agents for the treatment of central nervous system disorders associated with phosphodiesterase 10 (PDE10). The present invention also relates to the use of such compounds for treating neurological and psychiatric disorders, such as schizophrenia, psychosis or Huntington's disease, and those associated with striatal hypofunction or basal ganglia dysfunction.
