543719-46-6Relevant academic research and scientific papers
Synthesis of fused bicyclic imidazoles by ring-closing metathesis
Chen, Yingzhong,Dias, H. V. Rasika,Lovely, Carl J.
, p. 1379 - 1382 (2003)
The preparation of a number of dienylimidazole via chemoselective metal-halogen exchange and their utility in ring-closing metathesis is described. Essentially all regioisomeric permutations participate in metathesis with the notable exception of 4-vinyl-
Ring closing metathesis reactions of imidazole deriatives
Lovely, Carl J.,Chen, Yingzhong,Ekanayake, E. Vindana
, p. 873 - 894 (2008/09/18)
A series of diene substituted imidazole derivatives has been prepared from the corresponding haloimidazoles via halogen-magnesium exchange and electrophile quench. These derivatives were explored as susbstrates in a ring closing metathesis reaction, which was successful if the imidazolium ion was used. In addition, one successful example of a ring closing metathesis reaction of an enyne derivative was performed, with the resulting diene successfully engaging in a Diels-Alder reaction.
