543741-62-4Relevant academic research and scientific papers
Further improvements of the dibutyl tin oxide-catalyzed regioselective diol tosylation
Guillaume, Michel,Lang, Yolande
, p. 579 - 582 (2010)
In this Letter, we report that selective monotosylation of a 1,2-diol is possible using only 0.1 mol % of Bu2SnO. More interestingly, we found that the corresponding tin acetal 3b gave faster conversions and more reproducible reaction times. Moreover, the loading of this catalyst could be as low as 0.05-0.005 mol %.
PROCESS FOR REGIOSELECTIVE DIOL MONO-TOSYLATION USING CATALYTIC AMOUNTS OF A GENERIC DIALKYLTINACETAL
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Page/Page column 5-6, (2008/12/05)
The present invention concerns the use of dibutyl tin oxide for regioselective catalytic diol mono-tosylat ion at a concentration lower than 2 mol%. The present invention also concerns the use of a generic acetal compound of Formula (Ic) in a catalytic process for regioselective diol mono-tosylat ion, wherein Y is selected from the group of C1-6alkyl, phenyl and benzyl. The concentration of the generic acetal compound of Formula (Ic) is less than about 2 mol%, preferably ranges between about 2 mol% and about 0.0005 mol%, preferably ranges between about 0.1 mol% and about 0.005 mol%.
