54397-23-8 Usage
Uses
Used in Pharmaceutical Industry:
(R)-2-amino-2-(4-hydroxyphenyl)acetamide is used as an activated side chain precursor for the synthesis of various pharmaceutical compounds. Its role as an intermediate in the synthesis of 3-(4-Hydroxyphenyl)-2(1H)-pyrazinone (H951260) highlights its importance in the development of new drugs and potential impurities in existing medications.
Used in Antibiotic Production:
In the context of penicillin and related antibiotics, such as ampicillin and amoxicillin, (R)-2-amino-2-(4-hydroxyphenyl)acetamide is involved in the semi-synthetic preparation process. It may also be associated with the formation of impurities, such as 3-(4-Hydroxyphenyl)-2(1H)-pyrazinone, which can arise during the production or degradation of these antibiotics. This highlights the need for careful monitoring and control of the synthesis process to ensure the quality and safety of the final product.
Check Digit Verification of cas no
The CAS Registry Mumber 54397-23-8 includes 8 digits separated into 3 groups by hyphens. The first part of the number,starting from the left, has 5 digits, 5,4,3,9 and 7 respectively; the second part has 2 digits, 2 and 3 respectively.
Calculate Digit Verification of CAS Registry Number 54397-23:
(7*5)+(6*4)+(5*3)+(4*9)+(3*7)+(2*2)+(1*3)=138
138 % 10 = 8
So 54397-23-8 is a valid CAS Registry Number.
54397-23-8Relevant academic research and scientific papers
Preparation of some potential impurities of ampicillin and amoxicillin
Yongxin, Zhu,Roets, Eugene,Busson, Roger,Janssen, Gerard,Hoogmartens, Jos
, p. 67 - 72 (2007/10/03)
The preparation and characterization is described of some potential impurities of the penicillins ampicillin and amoxicillin, which have not been reported previously.These impurities may be formed during the semi-synthetic preparation of these antibiotics
Therapeutic L- and DL- phenylglycines to treat diseases or disorders of reduced blood flow or oxygen availability
-
, (2008/06/13)
L- and DL- Phenylglycines of the formula STR1 and pharmaceutically acceptable salts thereof, wherein R is hydrogen or methyl and R1 is NH2, OH or completes a carboxylic ester group, useful in treating certain cardiovascular diseases, diabetes and obesity.
