544-65-0

Usage

Uses

Used in Industrial Applications:
(E)-tetradec-4-enoic acid is used as a raw material for the production of plastics, lubricants, and surfactants due to its unique chemical properties and versatility in various manufacturing processes.
Used in Medical Research:
Erucic acid is used as a subject of study in the medical field for its potential to treat neurological disorders and as an anti-inflammatory agent, given its specific biochemical interactions and effects on the human body.
Used in Pharmaceutical Development:
Although not explicitly mentioned in the provided materials, erucic acid's potential health risks, such as its link to heart disease, make it a subject of interest for pharmaceutical development to better understand its effects and possibly mitigate or utilize these properties in drug design.
Regulated in Food Industry:
(E)-tetradec-4-enoic acid is used in the food industry with regulation, as its presence in certain levels has raised health concerns in some countries. This regulation ensures that the consumption of erucic acid in food products is controlled to minimize potential health risks.

Upstream product

• 112-31-2 caprinaldehyde 
• 17857-14-6 (3-carboxypropyl)(triphenyl)phosphonium bromide 
• 57-57-8 β-Propiolactone 
• 39691-62-8 nonylmagnesium bromide 
• 74-86-2 acetylene 

Downstream Products

• 42124-95-8 tetradecen-(4c)-oic acid-⁽¹⁾-(4-bromo-phenacyl ester) 

Relevant academic research and scientific papers

Design, synthesis and antimycobacterial activities of 1-methyl-2-alkenyl- 4(1H)-quinolones

A series of 23 new 1-methyl-2-alkenyl-4(1H)quinolones have been synthesized and evaluated in vitro for their antimycobacterial activities against fast growing species of mycobacteria, such as Mycobacterium fortuitum, M. smegmatis and M. phlei. The compounds displayed good to excellent inhibition of the growth of the mycobacterial test strains with improved antimycobacterial activity compared to the hit compound, evocarpine. The most active compounds, which possessed chain length of 11-13 carbons at position-2 displayed potent inhibitory effects with an MIC value of 1.0 mg/L. In a human diploid embryonic lung cell line, MRC-5 cytotoxicity assay, the alkaloids showed weak to moderate cytotoxic activity. Biological evaluation of these evocarpine analogues on the less pathogenic fast growing strains of mycobacteria showed an interesting antimycobacterial profile and provided significant insight into the structure-activity relationships.

ONE-POT SYNTHESIS OF (Z)-4-ALKENOIC ACIDS

The reaction of β-propiolactone with di-(Z)-1-alkenylcuprates, prepared from Grignard reagents, copper(I) iodide and acetylene, gave (Z)-4-alkenoic acids in high yields in one-pot operation.