5440-27-7Relevant academic research and scientific papers
Thiazolidinedione derivatives, their production and use
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, (2008/06/13)
The object of the present invention is to provide a new thiazolidinedione derivative exhibiting excellent hypoglycemic and hypolipidemic action. Thiazolidinedione derivative represented by the general formula: STR1 wherein n represents an integer from 1 t
Pharmacologically active peptides
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, (2008/06/13)
Compounds of the formula STR1 and pharmaceutically acceptable non-toxic acid addition salts thereof, in which R is hydrogen, methyl, ethyl, cyclopropylmethyl, or allyl; A is a residue of a D-amino acid selected from the group consisting of Ala, Abu, Nva, Val, Nle, Leu, Ile, Gly(Al), Gly(Cp), Met, Cys(Me), Met(O), Cys(Me) (O), Ser, Ser(Me), Thr, and Hse; R1 is hydrogen, C1 -C3 primary alkyl, cyclopropylmethyl, allyl, ethylthiomethyl, 2-fluoroethyl, or propargyl; X is fluoro, bromo, iodo, chloro, hydroxy, C1 -C3 alkyl, trifluoromethyl, or C1 -C2 alkoxy; and Z is methyl or ethyl; are useful analgesic agents.
Preparation, reduction chimique et electrochimique d'α-nitrostyrylcetones - synthese d'heterocycles azotes
Marcot, Bernard,Rabaron, Alain,Viel, Claude,Bellec, Christian,Deswarte, Stephane,Maitte, Pierre
, p. 1224 - 1234 (2007/10/02)
Nitration of styryl ketones with nitrogen peroxide leads to the corresponding α-nitroethylenic ketones in good yield.However, the presence of methoxy groups involves a nitration on the aromatic nucleus.LiAlH4 reduction of α-nitrostyrylketones yields the c
