5440-53-9

Basic information

• Product Name: diethyl 2-acetamido-2-[(2-methylphenyl)methyl]propanedioate
• Synonyms: diethyl 2-acetamido-2-[(2-methylphenyl)methyl]propanedioate
• CAS NO: 5440-53-9
• Molecular Formula: C₁₇H₂₃NO₅
• Molecular Weight: 321.37
• Mol File: 5440-53-9.mol
• Article Data: 5

Chemical Properties

• Boiling Point: 466.4°Cat760mmHg
• Flash Point: 235.9°C
• Appearance: /
• Density: 1.133g/cm³
• Vapor Pressure: 7.08E-09mmHg at 25°C
• Refractive Index: 1.51
• CAS DataBase Reference: diethyl 2-acetamido-2-[(2-methylphenyl)methyl]propanedioate(CAS DataBase Reference)
• NIST Chemistry Reference: diethyl 2-acetamido-2-[(2-methylphenyl)methyl]propanedioate(5440-53-9)
• EPA Substance Registry System: diethyl 2-acetamido-2-[(2-methylphenyl)methyl]propanedioate(5440-53-9)

Safety Data

• Hazardous Substances Data: 5440-53-9(Hazardous Substances Data)

Usage

InChI:InChI=1/C17H23NO5/c1-5-22-15(20)17(18-13(4)19,16(21)23-6-2)11-14-10-8-7-9-12(14)3/h7-10H,5-6,11H2,1-4H3,(H,18,19)

Upstream product

• 1068-90-2 2-acetylaminomalonic acid diethyl ester 
• 13433-00-6 diethyl aminomalonate hydrochloride 
• 89-92-9 2-methylbenzyl bromide 

Downstream Products

• 37439-96-6 2-Acetylamino-3-o-tolyl-propionic acid ethyl ester 
• 856571-23-8 2-{2-[(1H-indole-2-carbonyl)amino]benzoylamino}-3-o-tolylpropionic acid ethyl ester 
• 856571-04-5 2-(2-aminobenzoylamino)-3-o-tolylpropionic acid ethyl ester 
• 37447-32-8 2-Acetylamino-2-(2-methyl-benzyl)-malonic acid monoethyl ester 
• 5463-90-1 (+/-)-2-Acetamino-3-o-tolyl-propionsaeure 
• 22888-51-3 2-amino-3-(2-methylphenyl)propanoic acid 

Relevant articles and documents

Organocatalytic Enantioselective Addition of α-Aminoalkyl Radicals to Isoquinolines

With a dual organocatalytic system involving a chiral phosphoric acid and a dicyanopyrazine-derived chromophore (DPZ) photosensitizer and under the irradiation with visible light, an enantioselective Minisci-type addition of α-amino acid-derived redox-active esters (RAEs) to isoquinolines has been developed. A variety of prochiral α-aminoalkyl radicals generated from RAEs were successfully introduced on isoquinolines, providing a range of valuable α-isoquinoline-substituted chiral secondary amines in high yields with good to excellent enantioselectivities.

Palladium-catalyzed benzylation of active methine compounds without additional base: Remarkable effect of 1,5-cyclooctadiene

(Chemical Equation Presented) The palladium complex prepared from DPPF and Cp(η3-C3H5)Pd is an effective catalyst for the alkylation of active methine compounds with benzylic carbonates under neutral conditions. The additi

Substituted acetamidomalonic esters and DL-2-acetamido acids as antitumor agents.

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