54401-13-7Relevant academic research and scientific papers
Synthesis of Thiodisaccharides using Phase-transfer Catalysis
Chretien, Francoise,Cesare, Pierre Di,Gross, Bernard
, p. 3297 - 3300 (2007/10/02)
Synthesis of thiodisaccharides or thioglycosides was performed by phase-transfer catalysis using phosphonium or ammonium salts.Starting from glycosyl halides, reaction with Na2S gave the corresponding thiodisaccharides with inversion of configuration at the anomeric centre.With unstable glycosyl halides, a solid-liquid system was used.Unsymmetrical thiodisaccharides and 1-thioglycosides were prepared by reaction of glycosyl halides with thiolate or 1-thioglucose under p.t.c. conditions.
