54404-01-2

Basic information

• Product Name: Benzenethiol, 2-bromo-4-chloro-
• CAS NO: 54404-01-2
• Molecular Formula: C6H4BrClS
• Molecular Weight: 223.521
• Mol File: 54404-01-2.mol

Chemical Properties

• CAS DataBase Reference: Benzenethiol, 2-bromo-4-chloro-(CAS DataBase Reference)
• NIST Chemistry Reference: Benzenethiol, 2-bromo-4-chloro-(54404-01-2)
• EPA Substance Registry System: Benzenethiol, 2-bromo-4-chloro-(54404-01-2)

Safety Data

• Hazardous Substances Data: 54404-01-2(Hazardous Substances Data)

Upstream product

• 873-38-1 4-chloro-2-bromoaniline 
• 106-54-7 p-Chlorothiophenol 

Downstream Products

• 18587-38-7 5-(2-bromo-4-chloro-phenylsulfanyl)-3-methyl-4-nitro-isothiazole 
• 17801-94-4 2'-Brom-4'-chlor-4-hydroxy-2-nitro-diphenylsulfid 
• 17801-97-7 2'-Brom-4'-chlor-3-hydroxy-2-nitro-diphenylsulfid 
• 17801-93-3 2'-Brom-4'-chlor-4-isopropyloxy-2-nitro-diphenylsulfid 
• 36798-10-4 4-Benzyloxy-2'-bromo-4'-chloro-5-methoxy-2-nitro-diphenylsulfid 
• 36803-83-5 2'-Bromo-4'-chloro-4,5-dibenzyloxy-2-nitro-diphenylsulfid 
• 16762-88-2 4-Chlor-2-brom-2'-nitro-6'-isopropyloxy-diphenylsulfid 
• 17801-92-2 2'-Brom-4'-chlor-3-isopropyloxy-2-nitro-diphenylsulfid 
• 17801-95-5 2'-Brom-4'-chlor-4-methoxy-2-nitro-diphenylsulfid 
• 91267-80-0 2-Brom-4-chlor-2'-nitro-diphenylsulfid 
• 91805-30-0 2-Brom-4-chlor-5'-methoxy-2'-nitro-diphenylsulfid 
• 18587-41-2 5-(2-bromo-4-chloro-phenylsulfanyl)-3-methyl-isothiazol-4-ylamine 
• 18587-44-5 N-[5-(2-bromo-4-chloro-phenylsulfanyl)-3-methyl-isothiazol-4-yl]-formamide 
• 3926-67-8 8-Hydroxy-chlorpromazin 

Relevant articles and documents

Halogenated method of aromatic compound

The invention belongs to the field of organic synthesis, and particularly relates to synthesis of aromatic halogens, in particular to arylamine. The invention discloses a synthesis method of a corresponding ortho-halogenated product from aromatic compounds such as carbazole and phenol. The method comprises the following steps: adding a metal sulfonate salt catalyst, aromatic amine, carbazole, phenol and other hydrogen - heteroatom-containing aromatic compound reaction substrates, a halogenation reagent and a reaction solvent at a specific reaction temperature. After the drying agent is dried, the yield of the reaction product and the nuclear magnetic characterization determining structure are determined by column chromatography. The reaction product yield is determined by gas chromatography. By adopting the method, under the cheap metal salt catalyst, a plurality of ortho-substituted brominated and chloro products can be obtained with moderate to excellent yield.

BENZOTHIOPHENE SULFONAMIDES AND OTHER COMPOUNDS THAT INTERACT WITH GLUCOKINASE REGULATORY PROTEIN

The present invention relates to benzothiophene sulfonamides and other compounds that interact with glucokinase regulatory protein. In addition, the present invention relates to methods of treating type 2 diabetes, and other diseases and/or conditions where glucokinase regulatory protein is involved using the compounds, or pharmaceutically acceptable salts thereof, and pharmaceutical compositions that contain the compounds, or pharmaceutically acceptable salts thereof.

Copper-catalyzed cross-coupling interrupted by an opportunistic smiles rearrangement: An efficient domino approach to dibenzoxazepinones

Unexpected Smiles! An unusual and highly regioselective synthesis of dibenzoxazepinones by a domino sequence assisted by an unexpected Smiles rearrangement is reported. The process is effective on electronically differentiated phenols and shows a high tolerance to variation in the benzamide substituents. A plausible path for the reaction, supported by preliminary mechanistic data, is offered. Copyright