5441-01-0

Basic information

• Product Name: 2,2-dimethylpropyl 2-bromopropanoate
• Synonyms: Neopentyl 2-bromopropanoate
• CAS NO: 5441-01-0
• Molecular Formula: C₈H₁₅BrO₂
• Molecular Weight: 223.1075
• Mol File: 5441-01-0.mol
• Article Data: 1

Chemical Properties

• Boiling Point: 187.9°C at 760 mmHg
• Flash Point: 75.2°C
• Density: 1.255g/cm³
• Vapor Pressure: 0.614mmHg at 25°C
• Refractive Index: 1.458
• CAS DataBase Reference: 2,2-dimethylpropyl 2-bromopropanoate(CAS DataBase Reference)
• NIST Chemistry Reference: 2,2-dimethylpropyl 2-bromopropanoate(5441-01-0)
• EPA Substance Registry System: 2,2-dimethylpropyl 2-bromopropanoate(5441-01-0)

Safety Data

• Hazardous Substances Data: 5441-01-0(Hazardous Substances Data)

Usage

General Description

2,2-dimethylpropyl 2-bromopropanoate is a chemical compound with the molecular formula C7H13BrO2. It is an ester derived from 2-bromopropanoic acid and 2,2-dimethylpropyl alcohol. 2,2-dimethylpropyl 2-bromopropanoate is commonly used as a reagent in organic synthesis, particularly in the production of pharmaceuticals and other fine chemicals. It is a colorless liquid with a fruity odor, and it is flammable and potentially harmful if ingested, inhaled, or in contact with the skin. The main uses of 2,2-dimethylpropyl 2-bromopropanoate include its role as a building block in the creation of other chemical compounds and as a solvent in some industrial processes. Additionally, it has been studied for its potential medicinal properties.

Upstream product

• 75-84-3 2,2-dimethyl-propanol-1 
• 598-72-1 2-Bromopropionic acid 
• 563-76-8 α-bromopropionyl bromide 

Relevant articles and documents

Inclusion complexes of EMPO derivatives with 2,6-di-O-methyl-β- cyclodextrin: Synthesis, NMR and EPR investigations for enhanced superoxide detection

The free radical trapping properties of eight 5-alkoxycarbonyl-5-methyl-1- pyrroline N-oxide (EMPO) type nitrones and those of 5,5-dimethyl-1-pyrroline N-oxide (DMPO) were evaluated for trapping of superoxide anion radicals in the presence of 2,6-di-O-methyl-β-cyclodextrin (DM-β-CD). 1H-NMR titrations were performed to determine both stoichiometries and binding constants for the diamagnetic nitrone-DM-β-CD equilibria. EPR titrations were then performed and analyzed using a two-dimensional EPR simulation program affording 1: 1 and 1: 2 stoichiometries for the nitroxide spin adducts with DM-β-CD and the associated binding constants after spin trapping. The nitroxide spin adducts associate more strongly with DM-β-CD than the nitrones. The ability of the nitrones to trap superoxide, the enhancement of the EPR signal intensity and the supramolecular protection by DM-β-CD against sodium l-ascorbate reduction were evaluated. The Royal Society of Chemistry 2006.