54414-38-9

Usage

Uses

Used in Pharmaceutical Synthesis:
(3-(1H-pyrazol-1-yl)phenyl)MethanaMine is utilized as a key intermediate in the development of pharmaceuticals, owing to its ability to form more complex molecules that can exhibit therapeutic effects. Its incorporation into drug candidates can lead to the discovery of new treatments for various diseases.
Used in Agrochemical Development:
In the agrochemical industry, (3-(1H-pyrazol-1-yl)phenyl)MethanaMine serves as a crucial component in the synthesis of compounds designed to protect crops and enhance agricultural productivity. Its potential as a building block allows for the creation of novel agrochemicals with improved efficacy and selectivity.
Used in Organic Reactions:
(3-(1H-pyrazol-1-yl)phenyl)MethanaMine is employed as a reactant in various organic reactions, such as cycloaddition and cross-coupling, due to its reactive nature. These reactions can lead to the formation of new chemical entities with potential applications in material science, pharmaceuticals, and other industries.
Used in Biological Research:
(3-(1H-pyrazol-1-yl)phenyl)MethanaMine is also used in biological research as a tool to study its antitumor and antimicrobial properties. This research can contribute to the understanding of its mechanism of action and potential use in therapeutic applications, particularly in the development of new drugs to combat cancer and infectious diseases.

Upstream product

• 4443-71-4 3,4-benzo-1,2-epoxy-1,3-cycloheptadiene 

Relevant academic research and scientific papers

Substitution Reactions Under NH3 Chemical Ionization Conditions in cis-/trans-1,2-Dihydroxybenzosuberans

The nucleophilic substitution reaction under NH3 chemical ionization (CI) conditions in cis- and trans-1,2-dihydroxybenzosuberans (1-4) has benn studied with the help ND3 CI and metastable data.The results indicate that in the parent diols 1 (cis) and 2 (trans), the substitution ion, sH>+, is produced mainly by the loss of H2O from the + ion (SNi reaction) while in their 7-methoxy derivatives 3 and 4, the ion-molecule reaction between + and NH3 seems to be the major pathway for the formation of sH>+.The substitution ion from 1 and 2 and the + ion from trans-1-amino-2-hydroxybenzosuberan give similar collision-induced dissociation mass-analysed ion kinetic energy spectra.Interestingly, their diacetates do not undergo the substitution reaction.

BICYCLIC UREA, THIOUREA, GUANIDINE AND CYANOGUANIDINE COMPOUNDS USEFUL FOR THE TREATMENT OF PAIN

Compounds of Formula I: or stereoisomers, tautomers, or pharmaceutically acceptable salts, solvates or prodrugs thereof, wherein Ring A, Ring C and X are as defined herein, are inhibitors of TrkA kinase and are useful in the treatment of diseases which can be treated with a TrkA kinase inhibitor such as pain, cancer, inflammation/inflammatory diseases, neurodegenerative diseases, certain infectious diseases, Sjogren's syndrome, endometriosis, diabetic peripheral neuropathy, prostatitis and pelvic pain syndrome.

Compounds with Bridgehead Nitrogen. Part 47. The Reaction between trans-1-Aminobenzocycloalkan-2-ols and Formaldehyde

The reaction between trans-1-aminoindan-2-ol and formaldehyde and between trans-1-amino-1,2,3,4-tetrahydronaphthalen-2-ol and formaldehyde yields 5,r-5a,t-8a,13,c-13a,t-16a-hexahydro-8,16-methanodi-indenodioxadiazecine and 5,6,r-6a,c-9a,14,15,t-15a,t-18a-octahydro-9,18-methanodinaphthodioxadiazecine respectively whereas the reaction between trans-1-amino-2-hydroxy-6,7,8,9-tetrahydro-5H-benzocycloheptane and formaldehyde yields bis(1,3a,4,5,6,10b-hexahydro-2H-benzocycloheptoxazol-1-yl)methanes.