54422-49-0 Usage
Description
A glucosidic alkaloid, cadambine occurs in Anthocephalus cadamba. It forms
colourless crystals from EtOH and has a specific rotation of [α]D25 - 71 0. It has
been characterized as the crystalline tetraacetate with m.p. 149-151 ° C.
References
Brown, Fraser, Tetrahedron Lett., 1957 (1974)
Check Digit Verification of cas no
The CAS Registry Mumber 54422-49-0 includes 8 digits separated into 3 groups by hyphens. The first part of the number,starting from the left, has 5 digits, 5,4,4,2 and 2 respectively; the second part has 2 digits, 4 and 9 respectively.
Calculate Digit Verification of CAS Registry Number 54422-49:
(7*5)+(6*4)+(5*4)+(4*2)+(3*2)+(2*4)+(1*9)=110
110 % 10 = 0
So 54422-49-0 is a valid CAS Registry Number.
54422-49-0Relevant articles and documents
BIOGENETICALLY PATTERNED SYNTHESIS OF CADAMBINE
Brown, Richard T.,Duckworth, D. Malcolm,Santos, Cid A. M.
, p. 1987 - 1990 (1991)
We report the synthesis of the glucosidic indole alkaloid cadambine (5) in 48 percent yield from its biological precursor secologanin (1) in an intermolecular variant of the in vivo process where chemoselective and regioselective attack by tryptamine on a 3S-epoxide 11 yields the seven-membered azepine ring.
