5443-10-7

Basic information

• Product Name: 1,3-ditrityloxypropan-2-ol
• Synonyms: 1,3-ditrityloxypropan-2-ol
• CAS NO: 5443-10-7
• Molecular Formula: C₄₁H₃₆O₃
• Molecular Weight: 0
• Mol File: 5443-10-7.mol
• Article Data: 9

Chemical Properties

• Boiling Point: 699.1°C at 760 mmHg
• Flash Point: 376.6°C
• Appearance: /
• Density: 1.16g/cm³
• Vapor Pressure: 1.62E-20mmHg at 25°C
• Refractive Index: 1.625
• CAS DataBase Reference: 1,3-ditrityloxypropan-2-ol(CAS DataBase Reference)
• NIST Chemistry Reference: 1,3-ditrityloxypropan-2-ol(5443-10-7)
• EPA Substance Registry System: 1,3-ditrityloxypropan-2-ol(5443-10-7)

Safety Data

• Hazardous Substances Data: 5443-10-7(Hazardous Substances Data)

Usage

Chemical class

Alcohols

Common use

Protecting group for alcohols in organic synthesis

Application

Synthesis of pharmaceuticals and bioactive compounds

Unique feature

Trityl-protected hydroxyl group

Versatility

Building block in chemical synthesis

Additional uses

Production of esters and ethers

Reactivity

High

Stability

High

Safety concerns

Harmful if ingested, inhaled, or comes in contact with the skin

Safety measures

Proper handling and precautions required in laboratory or industrial settings

InChI:InChI=1/C41H36O3/c42-39(31-43-40(33-19-7-1-8-20-33,34-21-9-2-10-22-34)35-23-11-3-12-24-35)32-44-41(36-25-13-4-14-26-36,37-27-15-5-16-28-37)38-29-17-6-18-30-38/h1-30,39,42H,31-32H2

Upstream product

• 76-83-5 trityl chloride 
• 56-81-5 glycerol 
• 51621-38-6 2-stearoyloxy-1,3-bis-trityloxy-propane 

Downstream Products

• 854666-43-6 2-palmitoyloxy-1,3-bis-trityloxy-propane 
• 97488-33-0 2-lauroyloxy-1,3-bis-trityloxy-propane 
• 58377-22-3 2-(toluene-4-sulfonyloxy)-1,3-bis-trityloxy-propane 
• 16975-62-5 tritylglycerol 
• 97924-47-5 2-methoxy-1,3-bis-trityloxy-propane 
• 210760-39-7 3-Benzoyl-5-fluoro-1-(2-trityloxy-1-trityloxymethyl-ethyl)-1H-pyrimidine-2,4-dione 
• 596-31-6 methoxytriphenylmethane 
• 1611470-13-3 (2R,3R,4S,5S)-2-(1,3-bis(trityloxy)propan-2-yloxy)-5-((R)-2,2-dimethyl-1,3-dioxolan-4-yl)-4-(4-oxopentanoyloxy)tetrahydrofuran-3-yl benzoate 
• 59237-83-1 N-1-(bistrityloxymethyl)methyluracil 
• 191802-80-9 5-Methyl-1-(2-trityloxy-1-trityloxymethyl-ethyl)-1H-pyrimidine-2,4-dione 
• 942200-51-3 [2-(4-iodophenoxy)-3-(trityloxy)propoxy]-triphenylmethane 
• 688319-39-3 1,3-bis(triphenylmethoxy)-2-propanone 
• 210760-46-6 N-[2-(2-Trityloxy-1-trityloxymethyl-ethoxy)-pyrimidin-4-yl]-benzamide 
• 210760-40-0 3-Benzoyl-5-methyl-1-(2-trityloxy-1-trityloxymethyl-ethyl)-1H-pyrimidine-2,4-dione 

Relevant articles and documents

BORON CLUSTER-COUPLED COMPOUND

To provide a novel boron-containing compound which increases intratumorous accumulation and tumor retention, and is efficiently taken into a tumor cell.SOLUTION: The present invention relates to a compound represented by formula (I) in the figure or a salt thereof. [In the formula, X represents a divalent to pentavalent organic group; Y represents a linker structure; R represents a monovalent group comprising boron clusters; and n represents 2, 3, 4 or 5.SELECTED DRAWING: None

Total synthesis of fuzinoside

The first total syntheses of fuzinoside (1b) were achieved from d-galactose through two strategies (BCA and ABC) in 11 (total yield: 5.0%) and 15 (total yield: 3.7%) steps, respectively. Comparison of NMR data of synthetic compound 1b and those of the fuzinoside isolated from the lateral roots of Aconitum carmicaelii suggests that the structure reported in the literature1,2 might not be accurate. The synthetic fuzinoside (1b) exhibited moderate cardiac activity in the isolated bullfrog heart assay.

BIOMOLECULE LABELING REACTANTS BASED ON AZACYCLOALKANES AND CONJUGATES DERIVED THEREOF

This invention concerns novel labeling reactants based on azacycloalkanes, wherein a suitable group is linked to the molecule allowing introduction of the said molecules to bioactive molecules in solution or on solid phase.