54431-18-4Relevant articles and documents
Synthesis, computational studies and assessment of in vitro inhibitory activity of umbelliferon-based compounds against tumour-associated carbonic anhydrase isoforms IX and XII
Angeli, Andrea,Capasso, Clemente,De Luca, Laura,Del Prete, Sonia,Gitto, Rosaria,Mancuso, Francesca,Supuran, Claudiu T.
, p. 1442 - 1449 (2020/07/13)
Coumarins are widely diffused secondary metabolites possessing a plethora of biological activities. It has been established that coumarins represent a peculiar class of human carbonic anhydrase (hCA) inhibitors having a distinct mechanism of action involv
Photo-induced Reactions: Part IV-Studies on Photo Fries Migration of Some Coumarins
Kulshrestha, S.K.,Dureja, P.,Mukerjee, S.K.
, p. 1064 - 1067 (2007/10/02)
Photo-Fries migration as an alternative route to acylcoumarins has been investigated. 7-Acetoxy- and 7-furoyloxy-coumarins give 6-acylcoumarins as the major products in contrast to Lewis acid mediated Fries migration where 8-acyl derivatives are the major products.The benzoates on the other hand give 6- and 8-acylcoumarins in equal proportions.The method is not suitable for the preparation of long chain unsaturated acyl derivatives of coumarins because in such cases photolytic deesterification is the main route.