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N,7-dimethyl-7H-purin-6-amine, also known as 7-methylguanine or 7-MG, is a chemical compound belonging to the purine family. It is a derivative of guanine, a naturally occurring purine base found in DNA and RNA, with an additional methyl group attached to the nitrogen atom at position 7. This modification can affect the compound's chemical properties and interactions with other molecules. 7-MG is of interest in various fields, including biochemistry and pharmacology, due to its potential role in DNA repair mechanisms and its ability to act as an antimetabolite, which can inhibit the synthesis of DNA and RNA. The compound is also studied for its potential applications in cancer research and as a therapeutic agent.

5444-25-7

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5444-25-7 Usage

Check Digit Verification of cas no

The CAS Registry Mumber 5444-25-7 includes 7 digits separated into 3 groups by hyphens. The first part of the number,starting from the left, has 4 digits, 5,4,4 and 4 respectively; the second part has 2 digits, 2 and 5 respectively.
Calculate Digit Verification of CAS Registry Number 5444-25:
(6*5)+(5*4)+(4*4)+(3*4)+(2*2)+(1*5)=87
87 % 10 = 7
So 5444-25-7 is a valid CAS Registry Number.

5444-25-7Upstream product

5444-25-7Downstream Products

5444-25-7Relevant academic research and scientific papers

Purines. LX. Dimroth rearrangement and concomitant hydrolytic deamination of 7-alkyl-1-methyladenines

Fujii,Saito,Ii,Suzuki

, p. 382 - 384 (2007/10/02)

The Dimroth rearrangement of 7-alkyl-1-methyladenines (8) to produce 7- alkyl-N6-methyladenines (9) (63-72% yield) has been found to be accompanied with unusual hydrolytic deaminations to give 7-alkyl-1-methyl-hypoxanthines (10) (1-3.5%) and/or 7-alkylhypoxanthines (11) (12-22%), when effected in boiling H2O for 4-70 h. Probable pathways leading to these by-products are proposed.

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