54447-57-3 Usage
Description
Adenosine-5'-13C is a carbon-13 labeled analogue of adenosine, a purine nucleoside that plays a crucial role in various biochemical processes within living organisms. The presence of the carbon-13 isotope in this compound allows for enhanced detection and tracking in scientific research and medical applications due to its distinct nuclear magnetic resonance (NMR) properties.
Uses
Used in Pharmaceutical Industry:
Adenosine-5'-13C is used as a research tool for studying the metabolism and function of adenosine in biological systems. The carbon-13 labeling enables researchers to differentiate between the labeled compound and endogenous adenosine, providing valuable insights into adenosine's role in cellular processes.
Used in Medical Research:
Adenosine-5'-13C is used as a tracer molecule in medical research, particularly in the study of cardiovascular, neurologic, and renal functions. The carbon-13 isotope allows for the non-invasive tracking of adenosine's distribution, metabolism, and interaction with receptors in the body, which can help in understanding various diseases and developing targeted therapies.
Used in Biochemical Analysis:
Adenosine-5'-13C is used as a reference compound in biochemical analysis, where its distinct NMR signature can be used to calibrate instruments and ensure accurate measurements. This is particularly useful in the study of enzyme kinetics, where the labeled adenosine can be used to monitor enzyme activity and substrate specificity.
Used in Drug Development:
Adenosine-5'-13C is used as a starting material or intermediate in the synthesis of novel adenosine-based drugs. The carbon-13 labeling can aid in the structural elucidation of new compounds and help in optimizing their pharmacological properties, such as potency, selectivity, and stability.
Used in Diagnostic Imaging:
Adenosine-5'-13C can be used in the development of diagnostic imaging agents, particularly for magnetic resonance spectroscopy (MRS) and positron emission tomography (PET). The carbon-13 isotope provides a unique signature that can be detected and used to monitor the distribution and metabolism of the compound in vivo, which can be valuable in the diagnosis and monitoring of various diseases.
Check Digit Verification of cas no
The CAS Registry Mumber 54447-57-3 includes 8 digits separated into 3 groups by hyphens. The first part of the number,starting from the left, has 5 digits, 5,4,4,4 and 7 respectively; the second part has 2 digits, 5 and 7 respectively.
Calculate Digit Verification of CAS Registry Number 54447-57:
(7*5)+(6*4)+(5*4)+(4*4)+(3*7)+(2*5)+(1*7)=133
133 % 10 = 3
So 54447-57-3 is a valid CAS Registry Number.
54447-57-3Relevant articles and documents
Synthesis of {[A15-13C]5'-deoxy-N1-methyladenosylcobalamin+}Cl-
Brown, Kenneth L.,Xia, Zuping
, p. 635 - 643 (2007/10/03)
The synthesis of {[A15-13C]5'-deoxy-N1-methyladenosylcobalamin+}Cl-, an analog of coenzyme B12, was accomplished by glycosidation of [5-13C]D-ribose with 4-pentenol, followed by benzoylation, coupling
