2-amino-3-(toluene-4-sulfonyl)-propionic acid, also known as L-methionine sulfoximine (MSO), is a chemical compound with the molecular formula C10H12NO4S. It is a synthetic amino acid analog that acts as a potent and selective inhibitor of glutamine synthetase, an enzyme involved in the biosynthesis of glutamine. MSO is widely used in scientific research to study the role of glutamine in various biological processes, such as cell proliferation, protein synthesis, and nitrogen metabolism. Due to its ability to block glutamine synthesis, MSO has potential applications in cancer research and therapy, as it can selectively target cancer cells that rely heavily on glutamine for growth and survival. Additionally, MSO has been used as a tool to investigate the role of glutamine in neurotransmitter synthesis and other cellular functions.
5445-05-6
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Basic information
- Product Name: 2-amino-3-(toluene-4-sulfonyl)-propionic acid
- Synonyms:
- CAS NO:5445-05-6
- Molecular Formula:
- Molecular Weight: 243.284
- EINECS: N/A
- Product Categories: N/A
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Chemical Properties
- Melting Point: N/A
- Boiling Point: N/A
- Flash Point: N/A
- Appearance: N/A
- Density: N/A
- Refractive Index: N/A
- Storage Temp.: N/A
- Solubility: N/A
- CAS DataBase Reference: 2-amino-3-(toluene-4-sulfonyl)-propionic acid(CAS DataBase Reference)
- NIST Chemistry Reference: 2-amino-3-(toluene-4-sulfonyl)-propionic acid(5445-05-6)
- EPA Substance Registry System: 2-amino-3-(toluene-4-sulfonyl)-propionic acid(5445-05-6)
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Safety Data
- Hazard Codes: N/A
- Statements: N/A
- Safety Statements: N/A
- WGK Germany:
- RTECS:
- HazardClass: N/A
- PackingGroup: N/A
- Hazardous Substances Data: 5445-05-6(Hazardous Substances Data)
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5445-05-6 Usage
Chemical compound
2-amino-3-(toluene-4-sulfonyl)-propionic acidAlso known as
4-Tosyl-L-homoserineDerivative of
HomoserineFunction
Amino acid involved in the biosynthesis of methionineTosyl group
Derived from tosyl chloride, used for protection of amine and alcohol groups in organic synthesisPotential applications
Organic chemistry and biochemistryPossible uses
Development of new pharmaceuticals or other biologically active compounds.Check Digit Verification of cas no
The CAS Registry Mumber 5445-05-6 includes 7 digits separated into 3 groups by hyphens. The first part of the number,starting from the left, has 4 digits, 5,4,4 and 5 respectively; the second part has 2 digits, 0 and 5 respectively.Calculate Digit Verification of CAS Registry Number 5445-05:
(6*5)+(5*4)+(4*4)+(3*5)+(2*0)+(1*5)=86
86 % 10 = 6
So 5445-05-6 is a valid CAS Registry Number.
5445-05-6Upstream product
5445-05-6Downstream Products
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2-amino-3-(toluene-4-sulfonyl)-propionic acid
