5445-15-8

Usage

Uses

Used in Pharmaceutical Applications:
[[3-[(carbamothioylhydrazinylidene)methyl]phenyl]methylideneamino]thiourea is used as an active pharmaceutical ingredient for its potential therapeutic properties. Its specific functions and applications in this industry depend on its interactions with other chemicals and compounds, making it a valuable compound for drug development and research.
Used in Organic Synthesis:
In the field of organic synthesis, [[3-[(carbamothioylhydrazinylidene)methyl]phenyl]methylideneamino]thiourea serves as a key building block or intermediate in the creation of more complex organic molecules. Its unique structure allows for various chemical reactions, contributing to the synthesis of a wide range of compounds.
Used as a Reagent in Chemical Processes:
[[3-[(carbamothioylhydrazinylidene)methyl]phenyl]methylideneamino]thiourea is also employed as a reagent in various chemical processes. Its properties make it suitable for use in different reactions, facilitating the production of desired products and enhancing the efficiency of these processes.

Upstream product

• 626-19-7 Isophthalaldehyde 
• 79-19-6 thiosemicarbazide 

Downstream Products

• 1268364-67-5 C₁₆H₁₀F₆N₆S₂ 
• 1268364-68-6 C₂₀H₂₀N₆O₄S₂ 
• 1268364-66-4 C₂₂H₂₈N₆S₂ 
• 1268364-65-3 C₂₆H₁₈Cl₂N₆S₂ 

Relevant academic research and scientific papers

Thiosemicarbazones as Aedes aegypti larvicidal

Abstract A set of aryl- and phenoxymethyl-(thio)semicarbazones were synthetized, characterized and biologically evaluated against the larvae of Aedes aegypti (A. egypti), the vector responsible for diseases like Dengue and Yellow Fever. (Q)SAR studies were useful for predicting the activities of the compounds not included to create the QSAR model as well as to predict the features of a new compound with improved activity. Docking studies corroborated experimental evidence of AeSCP-2 as a potential target able to explain the larvicidal properties of its compounds. The trend observed between the in silico Docking scores and the in vitro pLC50 (equals -log LC50, at molar concentration) data indicated that the highest larvicidal compounds, or the compounds with the highest values for pLC50, are usually those with the higher docking scores (i.e., greater in silico affinity for the AeSCP-2 target). Determination of cytotoxicity for these compounds in mammal cells demonstrated that the top larvicide compounds are non-toxic.

Synthesis, molecular docking, acetylcholinesterase and butyrylcholinesterase inhibitory potential of thiazole analogs as new inhibitors for Alzheimer disease

A series of thirty (30) thiazole analogs were prepared, characterized by 1H NMR, 13C NMR and EI-MS and evaluated for Acetylcholinesterase and butyrylcholinesterase inhibitory potential. All analogs exhibited varied butyrylcholinester

Efficient synthesis of new tetradentate ligands with potential applications for 64Cu PET-imaging

We wish to report the synthesis of new tetradentate ligands in less than 3 h in good to excellent yields from a commercially available compound using microwave-assisted technology. First tests of complexation showed a high ability of these ligands to chel