54459-33-5

Basic information

• Product Name: Benzene, 1-butyl-2,4-dimethoxy-
• CAS NO: 54459-33-5
• Molecular Formula: C12H18O2
• Molecular Weight: 194.274
• Mol File: 54459-33-5.mol
• Article Data: 4

Chemical Properties

• CAS DataBase Reference: Benzene, 1-butyl-2,4-dimethoxy-(CAS DataBase Reference)
• NIST Chemistry Reference: Benzene, 1-butyl-2,4-dimethoxy-(54459-33-5)
• EPA Substance Registry System: Benzene, 1-butyl-2,4-dimethoxy-(54459-33-5)

Safety Data

• Hazardous Substances Data: 54459-33-5(Hazardous Substances Data)

Upstream product

• 151-10-0 1,3-Dimethoxybenzene 
• 109-69-3 n-Butyl chloride 
• 20469-63-0 1-iodo-2,4-dimethoxybenzene 
• 6703-00-0 1-(2,4-dimethoxyphenyl)butan-1-one 
• 613-45-6 2,4-Dimethoxybenzaldehyde 
• 96898-01-0 (2,4-dimethoxyphenyl)butene 
• 117705-67-6 1-(2,4-dimethoxyphenyl)-1-butanol 

Downstream Products

• 96897-99-3 3-butyl-2,6-dimethoxybenzoic acid 
• 81468-73-7 1-(5-butyl-2,4-dihydroxyphenyl)ethan-1-one 
• 117690-69-4 4-(4-cyanobutoxy)-5-butyl-2-hydroxyacetophenone 
• 117690-82-1 5-butyl-2,4-dimethoxyacetophenone 
• 856807-99-3 4-(5-butyl-2,4-dimethoxy-phenyl)-4-oxo-butyric acid 

Relevant articles and documents

Pd-catalyzed cross-electrophile Coupling/C-H alkylation reaction enabled by a mediator generatedviaC(sp3)-H activation

Transition-metal-catalyzed cross-electrophile C(sp2)-(sp3) coupling and C-H alkylation reactions represent two efficient methods for the incorporation of an alkyl group into aromatic rings. Herein, we report a Pd-catalyzed cascade cross-electrophile coupling and C-H alkylation reaction of 2-iodo-alkoxylarenes with alkyl chlorides. Methoxy and benzyloxy groups, which are ubiquitous functional groups and common protecting groups, were utilized as crucial mediatorsviaprimary or secondary C(sp3)-H activation. The reaction provides an innovative and convenient access for the synthesis of alkylated phenol derivatives, which are widely found in bioactive compounds and organic functional materials.

ANTI-INFLAMMATORY AGENTS

This invention provides benzene derivatives, pharmaceutical formulations of those derivatives, and a method of using the derivatives for the treatment of inflammation in mammals.