5446-36-6

Basic information

• Product Name: N-(4-methylphenyl)-5H-purin-6-amine
• CAS NO: 5446-36-6
• Molecular Formula: C₁₂H₁₁N₅
• Molecular Weight: 225.2492
• Mol File: 5446-36-6.mol
• Article Data: 2

Chemical Properties

• Boiling Point: 369.8°C at 760 mmHg
• Flash Point: 177.5°C
• Density: 1.38g/cm³
• Vapor Pressure: 1.15E-05mmHg at 25°C
• Refractive Index: 1.733
• CAS DataBase Reference: N-(4-methylphenyl)-5H-purin-6-amine(CAS DataBase Reference)
• NIST Chemistry Reference: N-(4-methylphenyl)-5H-purin-6-amine(5446-36-6)
• EPA Substance Registry System: N-(4-methylphenyl)-5H-purin-6-amine(5446-36-6)

Safety Data

• Hazardous Substances Data: 5446-36-6(Hazardous Substances Data)

Upstream product

• 540-23-8 p-toluidine hydrochloride 
• 68-94-0 hypoxanthine 
• 106-49-0 p-toluidine 
• 87-42-3 6-chloropurine 

Downstream Products

• 104091-28-3 (2R,4R,5S)-4-(6-p-Tolylamino-purin-9-yl)-tetrahydro-pyran-2,5-diol 
• 104091-18-1 (2S,4R,5S)-4-(6-p-Tolylamino-purin-9-yl)-tetrahydro-pyran-2,5-diol 

Relevant articles and documents

Microwave-assisted regioselective synthesis of acyclic nucleosides through an alkylating reaction with 2-oxa-1,4-butanediol diacetate

An efficient and green procedure for the synthesis of purine acyclic nucleosides through microwave-assisted, alkylation of various purine nucleobases with 2-oxa-1,4-butanediol diacetate in the absence of solvent and catalyst is described. The advantages of using this method include its environmental friendliness, simple manipulation, short reaction time, high regioselectivity, and good yields.