5447-52-9

Basic information

• Product Name: 2,5-bis(1,3-benzodioxol-5-ylmethylidene)cyclopentanone
• CAS NO: 5447-52-9
• Molecular Formula: C₂₁H₁₆O₅
• Molecular Weight: 348.3487
• Mol File: 5447-52-9.mol
• Article Data: 4

Chemical Properties

• Boiling Point: 572.5°C at 760 mmHg
• Flash Point: 253.7°C
• Density: 1.432g/cm³
• Vapor Pressure: 4.09E-13mmHg at 25°C
• Refractive Index: 1.727
• CAS DataBase Reference: 2,5-bis(1,3-benzodioxol-5-ylmethylidene)cyclopentanone(CAS DataBase Reference)
• NIST Chemistry Reference: 2,5-bis(1,3-benzodioxol-5-ylmethylidene)cyclopentanone(5447-52-9)
• EPA Substance Registry System: 2,5-bis(1,3-benzodioxol-5-ylmethylidene)cyclopentanone(5447-52-9)

Safety Data

• Hazardous Substances Data: 5447-52-9(Hazardous Substances Data)

Usage

Physical form

Yellow solid

Solubility

Insoluble in water, soluble in organic solvents

Uses

Building block for the creation of more complex organic compounds in organic synthesis and medicinal chemistry

Aromatic properties

Highly aromatic due to the presence of benzodioxole groups

Biological interactions

Potential for interactions with biological targets, making it a valuable tool in drug discovery and development research.

Upstream product

• 120-57-0 piperonal 
• 120-92-3 cyclopentanone 

Relevant articles and documents

Ash of pomegranate peels (APP): A bio-waste heterogeneous catalyst for sustainable synthesis of α,α′-bis(substituted benzylidine)cycloalkanones and 2-arylidene-1-tetralones

Abstract: α,α′-bis(substituted benzylidene)cycloalkanones were efficiently prepared from variously substituted aldehydes and cycloalkanones in water by using ash of pomegranate peels (APP) as a catalyst. The APP-catalyst was obtained from bio-waste by simple thermal treatment to dry peels of pomegranate fruit and formation of its active phase was confirmed by FT-IR, XRD, XRF, EDX, SEM, DSC-TGA and BET techniques. The analysis revealed that the present catalyst has basic sites which promote the synthesis of desired products. The main attractions of our protocol are utilization of highly abundant bio-waste-derived catalyst and good-to-excellent yield in shortest reaction time. This green protocol was further extended for structurally diverse 2-arylidene-1-tetralones by condensation of equimolar quantity of aromatic aldehydes and 1-tetralone at low temperature. The catalyst could be quantitatively recovered and reused effectively for five times. Graphic abstract: [Figure not available: see fulltext.].

Synthesis and fluorescence properties of α,α'-bis(substituted- benzylidene)cycloalkanones catalyzed by 1-methyl-3(2-(sulfooxy)ethyl)-1h- imidazol-3-ium chloride

-Bis(substituted-benzylidene)cycloalkanones were synthesized via a solvent-free cross-aldol condensation of aromatic aldehydes with cycloalkanones in the presence of a catalytic amount 1-methyl-3(2-(sulfooxy)ethyl)-1H-imidazol- 3-ium chloride at room temperature with excellent yields. The screening for optical properties indicated that the size of cycloalkanone has an influence on the fluorescence emission of products. Products coming from cyclohexanone have stronger fluorescence emission than those from cyclopentanone. Copyrigh